Department of Environmental and Radiological Health Sciences
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Faculty Research: Reproductive Biology & Neuroscience
Dr. Jerry Bouma
Assistant Professor, Biomedical Sciences
Email: Gerrit.Bouma@colostate.edu
Office Phone: (970) 491-8738
Faculty Profile
- PhD, Zoology, University of Idaho
- BS, Environmental Sciences, Van Hall Institute, The Netherlands
Projects in Dr. Bouma's laboratory are (1) to study the role of the transcription factor GATA4 in mammalian fetal ovarian development; (2) use the sheep and rabbit as a model to study the role of prenatal environmental toxicant exposure on testicular germ cell tumor development; (3) to investigate the role of pluripotency factors in the regulation of miRNAs in human ovarian cancer; and (4) to uncover the genetic network underlying mammalian fetal gonadal differentiation.
Dr. Marie E. Legare
Associate Director Education, Center for Environmental Medicine, Assistant Professor, Environmental and Radiological Health Sciences
Email: marie.legare@colostate.edu
Office Phone: (970) 491-7043
Faculty Profile
- PhD, Veterinary Anatomy, Texas A & M University
- DVM, Texas A & M University
- MS, Biomedical Science, Montana State University
- BS, Zoology, Montana State University
Dr. Legare’s research interest is in the analysis of genes and gene expression. She is interested in how lead, mercury, pesticide residues and other agents influence health and risk of disease. Her laboratory has several different projects on-going, including a March of Dimes grant to identify genes that are disregulated after exposure to alcohol. A second study is examining the exposure of embryonic stem cells to environmental chemicals and how genes are impacted.
Dr. Ronald B. Tjalkens
Associate Directory Research, Center for Environmental Medicine; Associate Professor, Environmental & Radiological Health Sciences
Email: ron.tjalkens@colostate.edu
Office Phone: (970) 491-7168
Faculty Profile
- PhD, Toxicology, University of Colorado Health Sciences Center
- BS, Chemistry/Biochemistry, University of California at San Diego
Research projects focus on neuroinflammatory mechanisms in neurodegenerative disorders, particularly disorders of the basal ganglia such as manganism and Parkinson’s disease. Specific areas of interest include inflammatory activation of microglia and astrocytes, astrocyte biology and calcium signaling, mitochondrial dysfunction, and molecular regulation of neuro-inflammatory genes. Approaches emphasize multi-dimensional fluorescence imaging, transgenic models, and molecular approaches to modulate gene expression in neural cells.
Dr. Quinton Winger
Assistant Professor, Biomedical Sciences
Email: quinton.winger@colostate.edu
Office Phone: (970) 491-7702
Faculty Profile
- PhD, Texas A&M University
- MS, University of Western Ontario
- BS, University of Western Ontario
Molecular techniques including gene “knock-out” and “gain-of-function” models are used to identify and characterize pathways necessary for proliferation, differentiation and pluripotency of trophoblast stem cells in healthy and abnormal placenta. A better understanding of trophoblast cell regulation in early pregnancy will improve the diagnosis, treatment and understanding of the environmental impacts of various reproductive diseases. Ultimately this research will reduce the number of premature births and improve fetal health.
Center for Environmental Medicine
Colorado State University
1681 Campus Delivery
Fort Collins, CO 80523-1681
Phone: (970) 491-8635
Fax: (970) 491-2940
cvmbs-cem@colostate.edu
