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Publications

Click "RESEARCH" to view Medline abstract from Entrez

 

RESEARCH Bergman N, Moraes KC, Anderson JR, Zaric B, Kambach C, Schneider RJ, Wilusz CJ, Wilusz J. (2007) Lsm proteins bind and stabilize RNAs containing 5' poly(A) tracts. Nat Struct Mol Biol. 14(9):824-831 
RESEARCH Kurt TD, Perrott MR, Wilusz CJ, Wilusz J, Supattapone S, Telling GC, Zabel MD, Hoover EA. (2007) Efficient in vitro amplification of chronic wasting disease PrPRES. J Virol. 81(17):9605-8 
REVIEW Garneau NL, Wilusz J, Wilusz CJ. (2007) The highways and byways of mRNA decay. Nat Rev Mol Cell Biol. 8(2):113-26 
REVIEW Wilusz CJ, Wilusz J. (2007) HuR-SIRT: the hairy world of posttranscriptional control. Mol Cell. 25(4):485-7. 
REVIEW Sokoloski KJ, Wilusz CJ, Wilusz J. (2006) Viruses: overturning RNA turnover. RNA Biol. 3(4):140-4. 
RESEARCH Anderson JR, Mukherjee D, Muthukumaraswamy K, Moraes KC, Wilusz CJ, Wilusz J. (2006) Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome. RNA. 12(10):1810-6.
RESEARCH Moraes K, Wilusz CJ, Wilusz J. (2006) CUG-BP binds to RNA substrates and recruits PARN deadenylase. RNA 12:1084-1091
RESEARCH Palaniswamy V, Moraes K, Wilusz CJ, Wilusz J. (2006) Nucleophosmin is selectively deposited on mRNA during polyadenylation. Nat. Struct. Mol. Biol. 13:429-435
RESEARCH

Hu J, Lutz CS, Wilusz J, Tian B. (2005) Bioinformatic identification of candidate cis-regulatory elements involved in human mRNA polyadenylation.
RNA. 11:1485-93.
REVIEW Wilusz CJ, Wilusz J (2005) Eukaryotic Lsm Proteins: lessons from bacteria. Nat. Struct. Mol. Biol. 12:1031-1036
RESEARCH
Opyrchal, M., Anderson, J.T., Sokoloski, K.J., Wilusz, C.J. and Wilusz, J. (2005) A cell-free mRNA stability assay reveals conservation of the enzymes and mechanisms of mRNA decay between mosquito and mammalian cell lines. Insect Biochemistry & Molecular Biology 35(12):1321-34
RESEARCH

Sachchithananthan M, Stasinopoulos SJ, Wilusz J, Medcalf RL. (2005) The relationship between the prothrombin upstream sequence element and the G20210A polymorphism: the influence of a competitive environment for mRNA 3'-end formation.
Nucleic Acids Res 33(3):1010-20.
RESEARCH Seal R, Temperley R, Wilusz J, Lightowlers RN, Chrzanowska-Lightowlers ZM. (2005) Serum-deprivation stimulates cap-binding by PARN at the expense of eIF4E, consistent with the observed decrease in mRNA stability. Nucleic Acids Res 33(1):376-87.
REVIEW Fritz DT, Bergman N, Kilpatrick WJ, Wilusz CJ, Wilusz J. (2004) Messenger RNA decay in Mammalian cells: the exonuclease perspective. Cell Biochem Biophys 41(2):265-78.
REVIEW Wilusz CJ, Wilusz J. (2004) Bringing the role of mRNA decay in the control of gene expression into focus. Trends Genet 20(10):491-7.
RESEARCH Milone J, Wilusz J, Bellofatto V. (2004) Characterization of deadenylation in trypanosome extracts and its inhibition by poly(A)-binding protein Pab1p. RNA 10(3):448-57.
RESEARCH Mukherjee D, Fritz DT, Kilpatrick WJ, Gao M, Wilusz J. (2004) Analysis of RNA exonucleolytic activities in cellular extracts. Methods Mol Biol 257:193-212.
RESEARCH Bergman N, Milone J, Bates EJ, Opyrchal M, Bellofatto V, Wilusz J. (2004) Assessing messenger RNA decapping in cellular extracts. Methods Mol Biol 257:181-92.
RESEARCH Kash JC, Cunningham DM, Smit MW, Park Y, Fritz DT, Wilusz J, Katze MG. (2002) Selective translation of eukaryotic mRNAs: functional molecular analysis of GRSF-1, a positive regulator of influenza virus protein synthesis. J Virol. 76(20):10417-26.
RESEARCH Milone J, Wilusz J, Bellofatto V. (2002) Identification of mRNA decapping activities and an ARE-regulated 3' to 5' exonuclease activity in trypanosome extracts. Nucleic Acids Res. 30(18):4040-50.
RESEARCH Natalizio BJ, Muniz LC, Arhin GK, Wilusz J, Lutz CS. (2002) Upstream elements present in the 3'-untranslated region of collagen genes influence the processing efficiency of overlapping polyadenylation signals. J Biol Chem. 277(45):42733-40. Epub 2002 Aug 27.
METHOD/RESEARCH Bergman N, Opyrchal M, Bates EJ, Wilusz J. (2002) Analysis of the products of mRNA decapping and 3'-to-5' decay by denaturing gel electrophoresis. RNA.;8(7):959-65.
RESEARCH Arhin GK, Boots M, Bagga PS, Milcarek C, Wilusz J. (2002) Downstream sequence elements with different affinities for the hnRNP H/H' protein influence the processing efficiency of mammalian polyadenylation signals. Nucleic Acids Res. 30(8):1842-50.
RESEARCH Mukherjee D, Gao M, O'Connor JP, Raijmakers R, Pruijn G, Lutz CS, Wilusz J. (2002) The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements. EMBO J. 21(1-2):165-74.
LETTER Schneider R, Agol VI, Andino R, Bayard F, Cavener DR, Chappell SA, Chen JJ, Darlix JL, Dasgupta A, Donze O, Duncan R, Elroy-Stein O, Farabaugh PJ, Filipowicz W, Gale M Jr, Gehrke L, Goldman E, Groner Y, Harford JB, Hatzglou M, He B, Hellen CU, Hentze MW, Hershey J, Hershey P, Hohn T, Holcik M, Hunter CP, Igarashi K, Jackson R, Jagus R, Jefferson LS, Joshi B, Kaempfer R, Katze M, Kaufman RJ, Kiledjian M, Kimball SR, Kimchi A, Kirkegaard K, Koromilas AE, Krug RM, Kruys V, Lamphear BJ, Lemon S, Lloyd RE, Maquat LE, Martinez-Salas E, Mathews MB, Mauro VP, Miyamoto S, Mohr I, Morris DR, Moss EG, Nakashima N, Palmenberg A, Parkin NT, Pe'ery T, Pelletier J, Peltz S, Pestova TV, Pilipenko EV, Prats AC, Racaniello V, Read GS, Rhoads RE, Richter JD, Rivera-Pomar R, Rouault T, Sachs A, Sarnow P, Scheper GC, Schiff L, Schoenberg DR, Semler BL, Siddiqui A, Skern T, Sonenberg N,Tahara SM, Thomas AA, Toulme JJ, Wilusz J, Wimmer E, Witherell G, Wormington M. (2001) New ways of initiating translation in eukaryotes. Mol Cell Biol. 21(23):8238-46.
RESEARCH Wilusz CJ, Gao M, Jones CL, Wilusz J, Peltz SW. (2001) Poly(A)-binding proteins regulate both mRNA deadenylation and decapping in yeast cytoplasmic extracts. RNA.7(10):1416-24.
RESEARCH Veraldi KL, Arhin GK, Martincic K, Chung-Ganster LH, Wilusz J, Milcarek C. (2001) hnRNP F influences binding of a 64-kilodalton subunit of cleavage stimulation factor to mRNA precursors in mouse B cells. Mol Cell Biol. 21(4):1228-38.
RESEARCH Evans D, Perez I, MacMorris M, Leake D, Wilusz CJ, Blumenthal T. (2001) A complex containing CstF-64 and the SL2 snRNP connects mRNA 3' end formation and trans-splicing in C. elegans operons. Genes Dev. 15(19):2562-71.
RESEARCH Gao M, Fritz DT, Ford LP, Wilusz J. (2000) Interaction between a poly(A)-specific ribonuclease and the 5' cap influences mRNA deadenylation rates in vitro. Mol Cell.
5(3):479-88.
METHOD/REVIEW Fritz DT, Ford LP, Wilusz J. (2000) An in vitro assay to study regulated mRNA stability.
Sci STKE. 2000(61):PL1.
METHOD/RESEARCH Bagga PS, Wilusz J. (1999) Northwestern screening of expression libraries. Methods Mol Biol. 118:245-56.
RESEARCH Park YW, Wilusz J, Katze MG. (1999) Regulation of eukaryotic protein synthesis: selective influenza viral mRNA translation is mediated by the cellular RNA-binding protein GRSF-1. Proc Natl Acad Sci U S A. 96(12):6694-9.
METHOD Ford LP, Wilusz J. (1999) An in vitro system using HeLa cytoplasmic extracts that reproduces regulated mRNA stability. Methods. 17(1):21-7.
RESEARCH Ford LP, Wilusz J. (1999) 3'-Terminal RNA structures and poly(U) tracts inhibit initiation by a 3'-->5' exonuclease in vitro. Nucleic Acids Res. 27(4):1159-67.
RESEARCH Ford LP, Watson J, Keene JD, Wilusz J. (1999) ELAV proteins stabilize deadenylated intermediates in a novel in vitro mRNA deadenylation/degradation system. Genes Dev. 13(2):188-201.
RESEARCH Bagga PS, Arhin GK, Wilusz J. (1998) DSEF-1 is a member of the hnRNP H family of RNA-binding proteins and stimulates pre-mRNA cleavage and polyadenylation in vitro. Nucleic Acids Res. 26(23):5343-50.
RESEARCH Chen F, Wilusz J. (1998) Auxiliary downstream elements are required for efficient polyadenylation of mammalian pre-mRNAs. Nucleic Acids Res. 26(12):2891-8.
RESEARCH Ford LP, Bagga PS, Wilusz J. (1997) The poly(A) tail inhibits the assembly of a 3'-to-5' exonuclease in an in vitro RNA stability system. Mol Cell Biol. 17(1):398-406.
RESEARCH Banga SS, Ozer HL, Wilusz J. (1996) Assignment of GRSF1 encoding a poly(A)+ mRNA binding protein to human chromosome 4q13. Cytogenet Cell Genet. (4):295-6.
RESEARCH Chen F, MacDonald CC, Wilusz J. (1995) Cleavage site determinants in the mammalian polyadenylation signal. Nucleic Acids Res. 23(14):2614-20
RESEARCH Bagga PS, Ford LP, Chen F, Wilusz J. (1995) The G-rich auxiliary downstream element has distinct sequence and position requirements and mediates efficient 3' end pre-mRNA processing through a trans-acting factor. Nucleic Acids Res. 23(9):1625-31.
RESEARCH Hubbard K, Dhanaraj SN, Sethi KA, Rhodes J, Wilusz J, Small MB, Ozer HL. (1995) Alteration of DNA and RNA binding activity of human telomere binding proteins occurs during cellular senescence. Exp Cell Res. 218(1):241-7.
RESEARCH MacDonald CC, Wilusz J, Shenk T. (1994) The 64-kilodalton subunit of the CstF polyadenylation factor binds to pre-mRNAs downstream of the cleavage site and influences cleavage site location. Mol Cell Biol. 14(10):6647-54.
RESEARCH Chou ZF, Chen F, Wilusz J. (1994) Sequence and position requirements for uridylate-rich downstream elements of polyadenylation signals. Nucleic Acids Res. 22(13):2525-31.
RESEARCH Qian Z, Wilusz J. (1994) GRSF-1: a poly(A)+ mRNA binding protein which interacts with a conserved G-rich element. Nucleic Acids Res. 22(12):2334-43.
RESEARCH Qian Z, Wilusz J. (1993) Cloning of a cDNA encoding an RNA binding protein by screening expression libraries using a northwestern strategy. Anal Biochem. 212(2):547-54.
RESEARCH Qian ZW, Wilusz J. (1991) An RNA-binding protein specifically interacts with a functionally important domain of the downstream element of the simian virus 40 late polyadenylation signal. Mol Cell Biol. 11(10):5312-20.
RESEARCH Takagaki Y, Manley JL, MacDonald CC, Wilusz J, Shenk T. (1990) A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes Dev.
4(12A):2112-20.
RESEARCH Wilusz J, Shenk T. (1990) A uridylate tract mediates efficient heterogeneous nuclear ribonucleoprotein C protein-RNA cross-linking and functionally substitutes for the downstream element of the polyadenylation signal. Mol Cell Biol. 10(12):6397-407.
RESEARCH Wilusz J, Shenk T, Takagaki Y, Manley JL. (1990) A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates. Mol Cell Biol. 10(3):1244-8.
RESEARCH Wilusz J, Pettine SM, Shenk T. (1989) Functional analysis of point mutations in the AAUAAA motif of the SV40 late polyadenylation signal. Nucleic Acids Res. 17(10):3899-908.
RESEARCH Wilusz J, Feig DI, Shenk T. (1988) The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites. Mol Cell Biol. 8(10):4477-83.
RESEARCH Wilusz J, Shenk T. (1988) A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif. Cell. 52(2):221-8.
RESEARCH Wilusz J, Keene JD. (1986) Autoantibodies specific for U1 RNA and initiator methionine tRNA. J Biol Chem. 261(12):5467-72.
RESEARCH Kiley MP, Wilusz J, McCormick JB, Keene JD. (1986) Conservation of the 3' terminal nucleotide sequences of Ebola and Marburg virus. Virology. 149(2):251-4.
RESEARCH Wilusz J, Youngner JS, Keene JD. (1985) Base mutations in the terminal noncoding regions of the genome of vesicular stomatitis virus isolated from persistent infections of L cells. Virology. 140(2):249-56.
RESEARCH Wilusz J, Keene JD. (1984) Interactions of plus and minus strand leader RNAs of the New Jersey serotype of vesicular stomatitis virus with the cellular La protein. Virology.
135(1):65-73.