2008

Dow S. Liposome-nucleic acid immunotherapeutics. 2008. Expert Opinion in Drug Delivery 122:16-24.
PMCID: Pending.
http://dx.doi:10.1517/17425247.5.1.11

Jones-Carson J, Laughlin J, Hamad MA, Stewart AL, Voskuil MI, and Vazquez-Torres A. 2008. Inactivation
of [Fe-S] Metalloproteins Mediates Nitric Oxide-Dependent Killing of Burkholderia mallei. PLoS ONE 3(4): e1976.
PMCID: 2276317.
http://dx.doi: 10.1371/journal.pone.0001976

Julander, J. G., R. Skirpstunas, V. Siddharthan, K. Shafer, J. D. Hoopes, D. F. Smee, and J. D. Morrey. 2008.
C3H/HeN mouse model for the evaluation of antiviral agents for the treatment of Venezuelan equine
encephalitis virus infection. Antiviral Res. 78(3):230-41. PMCID: 2396595.
http://dx.doi:10.1016/j.antiviral.2008.01.007

Morrey, J. D., V. Siddharthan, H. Wang, J. O. Hall, R. T. Skirpstunas, J. L. Nordstrom, S. Koenig, S. Johnson, and
M. S. Diamond. 2008. West Nile virus-induced acute flaccid paralysis is prevented by monoclonal antibody
treatment even after infection of spinal cord neurons. Journal of Neurovirology. (2):152-63. PMCID: Pending.
http://dx.doi: 10.1080/13550280801958930

McCollister, B.D., J.T. Myers, J. Jones-Carson, M. Husain, T.J. Bourret, and A. Vazquez-Torres. 2008. N2O3 enhances
the nitrosative potential of IFNy-primed macrophages in response to Salmonella. Immunobiol. 212:759-769.
PMCID: 2329578
http://dx.doi.org/10.1016/j.imbio.2007.09.019

Morrey, J.D., A.L. Olsen, V. Siddharthan, N.E. Motter, H. Wang, B.S. Taro, D. Chen, D. Ruffner, and J.O. Hall. 2008.
Increased blood-brain-barrier permeability not a primary determinant for lethality of West Nile virus infection of rodents.
J Gen Virol. 89:467-473. PMCID: Pending.
http://dx.doi.org/10.1099/vir.0.83345-0

Choi, K.-H., T. Mima, Y. Casart Quintero, D. Rholl, A. Kumar, I. Beacham and H.P. Schweizer. 2008. Genetic Tools for
select agent compliant manipulation of Burkholderia pseudomallei. Appl. Env. Microbiol.74(4):1064-75. PMCID: 2258562.
http://dx.doi.org/10.1128/AEM.02430-07 

Molins-Schneekloth C.R., J.T. Belisle, and J.M. Petersen. 2008. Genomic markers for differentiation of Francisella
tularensis subsp. tularensis A.I and A.II strains. Appl Environ Microbiol. 74(1):336-41. PMCID: 2223193.
http://dx.doi.org/10.1128/AEM.01522-07 

2007

Brennan, P.J. and D.C. Crick. 2007. The cell-wall core of Mycobacterium tuberculosis in the context of drug discovery.
Current Topics in Medicinal Chemistry. 7(5):475-488. PMCID: Pending.
http://dx.doi.org/10.2174/156802607780059763

Kurosu, M., S. Mahapatra, P. Narayanasamy and D.C. Crick. 2007. Chemoenzymatic synthesis of Park's nucleotide:
toward the development of high-throughput screening for MraY inhibitors. Tetrahedron Lett. 48:799-803.
http://dx.doi.org/10.1016/j.tetlet.2006.11.160 

Kurosu, M., P. Narayanasamy, and D.C. Crick. 2007. Synthetic studies toward the generation of uridine-amino alcohol-based
small optimized libraries. Heterocycles 72:339-352.
www.heterocycles.com 

Eoh, H. J., A.C. Brown, L. Buetow, W.N. Hunter, T. Parish, D. Kaur, P.J. Brennan and D.C. Crick. 2007. Characterization of the
Mycobacterium tuberculosis 4-diphosphocytidyl-2-C-methyl-D-erythritol synthase: Potential for drug development.
J. Bact. 189(24):8922-8927. PMCID: 2168624.
http://dx.doi.org/10.1128/JB.00925-07 

Barry, C.E., D.C. Crick and M.R. McNeil. 2007. Targeting the Formation of the Cell Wall Core of Mycobacterium tuberculosis.
Infectious Disorders - Drug Targets, 7:182-202. PMCID: Pending.
http://bentham.org/cdtid/contabs/cdtid7-2.htm#10

Bosio, C.M., H. Bielefeldt-Ohmann and J.T. Belisle. 2007. Active suppression of the pulmonary immune response by
Francisella tularensis Schu4. J. Immunol. 178:4538-4547. PMCID: Pending.
http://www.jimmunol.org/cgi/content/full/178/7/4538 

Sundaresh, S., A. Randall, B. Unal, J.M. Petersen, J.T. Belisle, M.G. Hartley, M. Duffield, R.W. Titball, D.H. Davies, P.L. Felgner
and P. Baldi. 2007. From protein microarrays to diagnostic antigen discovery: a study of the pathogen Francisella tularensis.
Bioinformatics. 23(13):i508-518. PMCID: Pending.
http://dx.doi.org/10.1093/bioinformatics/btm207

Korbsrisate, S., A.P. Tomaras, S. Damnin, J. Ckumdee, V. Srinon, I. Lengwehasatit, M.L. Vasil and S. Suparak. 2007.
Characterization of two distinct phospholipase C enzymes from Burkholderia pseudomallei. Microbiology. 53(Pt 6): 1907-15.
PMCID: Pending.
http://dx.doi.org/10.1099/mic.0.2006/003004-0

Pierro, D.J., E. Powers and Olson, K.E. 2007. Genetic determinants of Sindbis virus strain TR339 affecting midgut infection
in the mosquito, Aedes aegypti. J. Gen. Virol. 88:1545-1554. PMCID: Pending.
http://dx.doi.org/10.1099/vir.0.82577-0

Morrey, J.D., V. Siddharthan, A.L. Olsen, H. Wang, J.G. Julander, J.O. Hall, H. Li, J.L. Nordstrom, S. Koenig, S. Johnson
and M.S. Diamond. 2007. Defining limits of treatment with humanized neutralizing monoclonal antibody for West Nile virus neurological
infection in a hamster model. Antimicrob Agents Chemother 51:2396-402. PMCID: 2168624.
http://dx.doi.org/10.1128/AAC.00147-07

Olsen, A.L., J.D. Morrey, D.F. Smee and R.W. Sidwell. 2007. Correlation between breakdown of the blood-brain-barrier and
disease outcome of viral encephalitis in mice. Antiviral Res. 75:14-19. PMCID: 2040264.
http://dx.doi.org/10.1016/j.antiviral.2006.11.013

Samuel, M.A., H. Wang, V. Siddharthan, J.D. Morrey and M.S. Diamond. 2007. Axonal transport mediates West Nile virus entry
into the central nervous system and induces acute flaccid paralysis. PNAS. 104(43):17140-17145. PMCID: 2040476.
http://dx.doi.org/10.1073/pnas.0705837104

Julander, J.G., V. Siddharthan, L.M. Blatt, K. Schafer, R.W. Sidwell and J.D. Morrey. 2007. Effect of exogenous interferon and an
interferon inducer on western equine encephalitis virus disease in a hamster model. Virology. 360(2):454-460. PMCID: 2040270.
http://dx.doi.org/10.1016/j.virol.2006.10.031

Guthery, S.L., B.A. Salisbury, M.S. Pungliya , J.C. Stephens and M. Bamshad. 2007. The structure of common genetic variation in
U.S. populations. Am J Hum Genet. 81(6):1221-1231. PMCID: 2276358.
http://dx.doi.org/10.1086/522239

Raghavan, R., S.R. Miller, L.D. Hicks and M.F. Minnick. 2007. The unusual 23S rDNA of Coxiella burnetii: two self-splicing group I
introns flank a 34-bp exon and one element lacks the canonical omega G. J. Bacteriol.189(18):6572-9. PMCID: 2045182.
http://dx.doi.org/10.1128/JB.00812-07 

Lubick, K., M. Radke, and M.A. Jutila. 2007. Securinine, a GABAa receptor antagonist, enhances macrophage clearance of phase II
C. burnetii: comparison with TLR agonists. J. Leuk. Biol. 82:1062-1069. PMCID Pending.
http://dx.doi.org/10.1189/jlb.0407255 

Ochoa-Repáraz, J., J. Sentissi, T. Trunkle, and D.W. Pascual. 2007. Attenuated Coxiella burnetii phase II causes a febrile response
in IFN-y-/- and TLR2-/- mice and protects against re-infection. Infect. Immun. 75:5845-5858. PMCID: 2168348.
http://dx.doi.org/10.1128/IAI.00901-07 

Yang, X., B.J. Hinnebusch, T. Trunkle, C.M. Bosio, Z. Suo, M. Tighe, A. Harmsen, T. Becker, K. Crist, N. Walters, R. Avci and D.W. Pascual.
2007. Oral Vaccination with Salmonella Simultaneously Expressing Yersinia pestis F1 and V Antigens Protects against Bubonic and
Pneumonic Plague. J Immunol. 178(2):1059-67. PMCID: Pending.
http://www.jimmunol.org/cgi/content/full/178/2/1059 

Tonge, Peter J., Caroline Kisker and Richard A. Slayden. 2007. Development of Modern InhA Inhibitors to Combat Drug Resistant Strains
of Mycobacterium tuberculosis. Current Topics in Medicinal Chemistry. 7(5): 489-498. PMCID: Pending.
http://dx.doi.org/10.2174/156802607780059781

Gundlapalli, A.V., J. Olson, S.P. Smith, M. Baza, R.R. Hausam, L.J. Eutropius, S.L. Pestotnik, K. Duncan, N. Staggers, P. Pincetl and M.H. Samore.
2007. Hospital Electronic-Record Based Public Health Surveillance System Deployed During the 2002 Winter Olympic Games. Am J Infect Control.
35:163-71. PMCID: Pending.
http://dx.doi.org/10.1016/j.ajic.2006.08.003

Jones-Carson, J., B.D. McCollister, E.T. Clambey and A. Vazquez-Torres. 2007. Systemic CD8 T-cell memory response to a Salmonella
Pathogenicity Island 2 effector is restricted to Salmonella enterica encountered in the gastrointestinal mucosa. Infection and Immunity
75(6):2708-16. PMCID: 1932863.
http://dx.doi.org/10.1128/IAI.01905-06

Fink, R.C., M.R. Evans, S. Porwollik, A. Vazquez-Torres, J. Jones-Carson, S.J. Libby, M. McClelland and H.M. Hassan. 2007. FNR is a global
regulator of anaerobic metabolism and virulence in Salmonella enterica serovar Typhimurium (ATCC 14028s) J. Bacteriol. 189: 2262-73.
PMCID: 1899381.
http://dx.doi.org/10.1128/JB.00726-06

McCollister, B.D., J.T. Myers, D.R. Voelker, J. Jones-Carson and A. Vazquez-Torres. 2007. Constitutive acid sphingomyelinase activity enhances
early and late macrophage killing of Salmonella enterica serovar Typhimurium. Infection and Immunity. 75:5346-5352. PMCID: 2168317.
http://dx.doi.org/10.1128/IAI.00689-07

Agnihothram, S.S., J. York, M. Trahey, and J.H. Nunberg. 2007. Bitopic membrane topology of the stable signal peptide in the tripartite Junín virus
GP-C envelope glycoprotein complex. J Virology 81:4331-7. PMCID: 1866146.
http://dx.doi.org/10.1128/JVI.02779-06

Radoshitzky, S.R., J. Abraham, C.F. Spiropoulou, J.H. Kuhn, D. Nguyen, W. Li, J. Nagel, P.J. Schmidt, J.H. Nunberg, S. Kunz, N.C. Andrews, M. Farzan
and H. Choe. 2007. Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses. Nature, 446:92-6. PMCID: Pending.
http://dx.doi.org/10.1038/nature05539

York, J., and J.H. Nunberg. 2007. A novel zinc-binding domain is essential for formation of the functional Junin virus envelope glycoprotein complex.
J.Virol. 81(24);13385-13391. PMCID: 2168868.
http://dx.doi.org/10.1128/JVI.01785-07

Boyne, M.E., T.J. Sullivan, C.W. amEnde, H. Lu, V. Gruppo, D. Heaslip, A. Amin, D. Chatterjee, A. Lenaerts, P.J. Tonge and R.A. Slayden. 2007.
Targeting fatty acid biosynthesis for the development of novel chemotherapeutics against Mycobacterium tuberculosis: Evaluation of A-ring
modified diphenyl ethers as high affinity InhA inhibitors. Antimicrobial Agents and Chemotherapy. 51(10):3562-3567. PMCID: 2043287.
http://dx.doi.org/10.1128/AAC.00383-07

Huang, Q., P.J. Tonge, R.A. Slayden, T. Kirikae and I. Ojima. 2007. FtsZ: A Novel Target for Tuberculosis Drug Discovery. Current Topics in
Medicinal Chemistry. 7(5): 527-543. PMCID: Pending.
http://dx.doi.org/10.2174/156802607780059790

Guthery, S.L. and M. Bamshad. 2007. Race, Genetics, and Medicine: Do the color of a leopard’s spots matter? Curr Opin Pediatr. 19(6):613-618.
PMCID: Pending.
http://www.co-pediatrics.com

2006

Kurosu, M. and D.C. Crick. 2006. A novel strategy for oligopeptide synthesis using a polymer-supported ammonium fluoride. Tetrahedron Lett.
47: 5325-5328.
http://dx.doi.org/10.1016/j.tetlet.2006.05.129

Kurosu, M., S.S. Dey and D.C. Crick. 2006. Efficient synthesis of tertiary amines from secondary amines. Tetrahedron Lett. 47: 4871-4875.
http://dx.doi.org/10.1016/j.tetlet.2006.05.038

Eoh, H. J., A.C. Brown, L. Buetow, W.N. Hunter, T. Parish, D. Kaur, P.J. Brennan and D.C. Crick. 2006. Characterization of
4-diphosphocytidyl-2-C-methyl-D-erythritol synthase (IspD) from Mycobacterium tuberculosis. FASEB JOURNAL 20 (4): A488-A488.
http://www.fasebj.org

Kumar, A., K.-L. Chua, and H.P. Schweizer. 2006. Method for regulated expression of single-copy efflux pump genes in a surrogate Pseudomonas
aeruginosa strain: Identification of the BpeEF-OprC chloramphenicol and trimethoprim efflux pump of Burkholderia pseudomallei 1026b. Antimicrob
Agents Chemother. 50:3460–3463. PMCID: 1610100.
http://dx.doi.org/10.1128/AAC.00440-06

Choi, K.-H., D. DeShazer and H.P. Schweizer. 2006. mini-Tn7 insertion in bacteria with multiple glmS-linked attTn7 sites: example Burkholderia mallei
ATCC 23344. Nature Protocols 1:162-169. PMCID: Pending.
http://dx.doi.org/10.1038/nprot.2006.25

Julander, J.G., J.D. Morrey, L.M. Blatt, K. Shafer, and R.W. Sidwell. 2006. Comparison of the inhibitory effects of interferon alfacon-1 and ribavirin on yellow
fever virus infection in a hamster model. Antiviral Res 73:140-6. PMCID: 1828627.
http://dx.doi.org/10.1016/j.antiviral.2006.08.008

Samuel, M.A., J.D. Morrey, and M.S. Diamond. 2006. Caspase-3 dependent cell death of neurons contributes to the pathogenesis of West Nile virus
encephalitis. J Virol 81:2614-23. PMCID: 1866006.
http://dx.doi.org/10.1128/JVI.02311-06

Morrey, J.D., V. Siddharthan, A.L. Olsen, G.Y. Roper, H.C. Wang, T.J. Baldwin, S. Koenig, S. Johnson, J.L. Nordstrom, and M.S. Diamond. 2006. Humanized
monoclonal antibody against West Nile virus E protein administered after neuronal infection protects against lethal encephalitis in hamsters. Journal of
Infectious Disease. 194:1300-08. PMCID: Pending.
http://dx.doi.org/10.1086/508293

Zaks, K., M. Jordan, A. Guth, K. Sellins, R. Kedl, A. Izzo, C. Bosio and S. Dow. 2006. Efficient immunization and cross-priming by vaccine adjuvants containing
TLR3 or TLR9 agonists complexed to cationic liposomes. J Immunol. 176(12):7335-45. PMCID: Pending.
http://www.jimmunol.org/cgi/content/abstract/176/12/7335

York, J. and J.H. Nunberg. 2006. Role of the stable signal peptide of Junín arenavirus envelope glycoprotein in pH-dependent membrane fusion. J. Virology 80:7775-80.
PMCID: 1563716.
http://dx.doi.org/10.1128/JVI.00642-06

York, J. and J.H. Nunberg. 2006. Distinct requirements for signal peptidase processing and function of the stable signal peptide subunits of the Junín virus
envelope glycoprotein. Virology 359: 72-81. PMCID: Pending.
http://dx.doi.org/10.1016/j.virol.2006.08.048

Agnihothram, S.S., J. York, and J.H. Nunberg. 2006. Role of the stable signal peptide and cytoplasmic domain of G2 in regulating intracellular transport of the
Junín virus envelope glycoprotein complex. J. Virology 80:5189-98. PMCID: 1472124.
http://dx.doi.org/10.1128/JVI.00208-06

2005

York, J., S.S. Agnihothram, V. Romanowski and J.H. Nunberg. 2005. Genetic analysis of heptad-repeat regions in the G2 fusion subunit of the Junín arenavirus
envelope glycoprotein. Virology 343:267-79. PMCID: Pending.
http://dx.doi.org/10.1016/j.virol.2005.08.030

2004

York, J., V. Romanowski, M. Lu and J.H. Nunberg. 2004 The signal peptide of the Junín arenavirus envelope glycoprotein is myristoylated and forms an essential
subunit of the mature G1-G2 complex. J. Virology 78:10783-10792. PMCID: 516395.
http://dx.doi.org/10.1016/j.virol.2005.08.030