EJ Ehrhart
Associate Professor
Residency Program Coordinator
Phone: 297-4086
Fax: 491-0603
Email:
EJ.Ehrhart@colostate.edu
Office: Animal Cancer Center, VTH
Lab: 252 Animal Cancer Center, VTH
Degrees
- University of Missouri, Columbia MO, BS, Animal Sciences, 1984
- University of Missouri, Columbia MO, DVM, Veterinary Medicine, 1987
- Colorado State University, Fort Collins CO, Residency, Anatomic Pathology, 1994
- Colorado State University, Fort Collins CO, PhD/Post Doc, Radiation Biology, 1996
Board Certifications
- American College of Veterinary Pathologists, Diplomate, 1998
Diagnostic Pathology Interests
- Oncological pathology
- Ophthalmological pathology
Research Interests
- Interest is in the study of proteins and protein signaling, also known as proteomics. The Comparative Pathology and Proteomics Laboratory researches the role of proteins in health and cancer.
- We study the proteins that differ between normal and cancerous tissue to tell us which proteins have become dysregulated. The proteins unique to a certain tumor (tumor markers) can be used as a means to more accurately diagnose the tumor and predict it's behavior. These unique proteins can also be used as targets for cancer therapy allowing for treatments to be personalized for each specific tumor and individual.
Selected Publications
Pub Med for Ehrhart EJ.
- N. Ehrhart, S.J. Withrow, R.C. Straw, E.J. Ehrhart, R.L. Page, H.L. Hottinger, K.A. Hahn, W.B. Morrison, M.R. Albrecht, C.S. Hedlund, A.S. Hammer, D.L. Holmberg, A.S. Moore, R.R. King, J.S. Klausner. Primary rib tumors in 54 dogs. Journal of the American Animal Hospital Association 31(1):65-69,1995.
- M.H. Barcellos-Hoff, E.J. Ehrhart, M. Kalia, R. Jirtle, K. Flanders, M.L.Tsang. Immunohistochemical detection of active TGFß in situ using engineered tissue. American Journal of Pathology 147(5):1228-1237, 1995.
- E.J. Ehrhart, E.L. Gillette, M.H. Barcellos-Hoff. Immunohistochemical evidence of rapid extracellular matrix remodeling following Fe particle irradiation of mouse mammary gland. Radiation Research 145(2):157-162, 1996.
- N. Ehrhart, S.J. Withrow, E.J. Ehrhart, J.H. Wimsatt. Insulin secreting tumor in the ferret: A retrospective study. Journal of the American Veterinary Medical Association 209(10); 15:1737-1740, 1996.
- E.J. Ehrhart, P. Segarini, M. L.-S. Tsang, A.G. Carroll, M.H. Barcellos-Hoff. Latent transforming growth factor ß1 activation in situ: quantitative and functional evidence after low-dose gamma-irradiation. Federation of American Societies for Experimental Biology (FASEB) 11(12):991-1002, 1997.
- N. Ehrhart, W.S. Dernell, E.J. Ehrhart, J.M. Hutchison, E.B. Douple, J.H. Brekke, R.C. Straw, S.J. Withrow. The effects of a controlled-release cisplatin delivery system (OPLAR-Pt) after marginal resection of mouse mammary carcinoma. American Journal of Veterinary Research 60(11):1347-1351, 1999.
- S.S. Tunev, E.J. Ehrhart§, H.E. Jensen, J.H. Foreman, R.-A. Richter, J.B. Messick. Necrotizing mycotic vasculitis with cerebral infarction caused by Aspergillus niger in a horse with acute typhlocolitis. Veterinary Pathology 36(4):347?51, 1999. §corresponding author.
- R.E. Guzman, E.J. Ehrhart, K. Wasson, J.J. Andrews. Primary hepatic hemangiosarcoma with pulmonary metastasis in a New Zealand white rabbit. Journal of Veterinary Diagnostic Investigation, 12:284-286, 2000. corresponding author.
- S.M. Aquino, R.E. Hamor, V.E. Valli, B.E. Kitchell, S.S. Tunev, K.L. Bailey, E.J. Ehrhart. Progression of an orbital T-cell rich B-cell lymphoma to a B-cell lymphoma in a dog. Veterinary Pathology, 37:465-469, 2000.
- N. Ehrhart, E.J. Ehrhart, J.S. Willis, D. Sisson, P. Constable, C.L. Greenfield, S. Manfra-Marretta, J. Hintermeister. Analysis of factors affecting survival in dogs with aortic body tumors. Veterinary Surgery, 31:44-8, 2002.
- S. Sulaimon, B.E. Kitchell, E.J. Ehrhart§. Immunohistochemical detection of melanoma specific antigens in spontaneous canine melanoma. Journal of Comparative Pathology, J Comp Pathol, 127 (2-3): 162-8, 2002. § corresponding author.
- J. Liptak, E.J. Ehrhart. Retroperitoneal sarcoma in 14 dogs. Journal of the American Veterinary Medical Association, accepted for publication, 6/2003.
- E.J. Ehrhart, R.E. Hamor, T. Turner, K.L. Bailey. Orbital liposarcoma in dogs. Veterinary Pathology. Veterinary Pathology, 2002. Submitted.
- E.J. Ehrhart, N.E. Mateus-Pinilla, N. Ehrhart. Immunohistochemical characterization of melan A and S100 antibodies in canine melanomas. Veterinary Pathology, 2002. Submitted..
- Book Chapter: R. Hamor, E.J. Ehrhart. Eye. In: Textbook of Veterinary Histology, edited by H.D. Dellmann, J. Eurell, 6th edn., Williams and Wilkins, Baltimore, MD. In print.