Vol. 14 | No. 1
MIP Struts its Stuff at the 2017 CVMBS Research Day
Check out more photos here.
Congratulations to the following Micro Undergraduates who performed at a stellar level this past semester:
Megan Kosovski recently joined the MIP academic advising team at CSU as an Academic Success Coordinator. Megan holds a Bachelor of Arts in English and Communication and a Master of Arts in Communication from the University of Illinois at Urbana-Champaign. Megan’s passion for higher education began with her career as an advisor and instructor at the University of Illinois and now continues in the MIP Department at CSU. She is thrilled to be a part of a department that is truly invested in making a difference in the lives of its students and the communities in which they live, study, and thrive. When she is not advising or missing the cornfields of Illinois, Megan can be found baking, hanging out with friends, playing poker, and exploring Fort Collins with her husband Jason, and their dogs, Vegas and Domino.
Transient In Vivo Resistance Mechanisms of Burkholderia pseudomallei to Ceftazidime and Molecular markers for Monitoring Treatment Response
Jason Cummings and Ric Slayden
At some point in their lives, every member of the academic research community has probably heard the question ‘when are you going to get out of a university and enter the REAL world’? After reading this month’s MIPub of the Month®, we think we finally figured out what they mean. They aren’t referring to an academic scientist’s employment and life experience, they are actually suggesting that we stop studying bacteria grown on artificial media in plastic dishes in a lab and start studying bacterial growth in REAL hosts like mammals.
MIP Publications January 2017
Susta L, He Y, Hutcheson JM, Lu Y, West FD, Stice SL, Yu P, Abdo Z, Afonso CL. Derivation of chicken induced pluripotent stem cells tolerant to Newcastle disease virus-induced lysis through multiple rounds of infection. Virol J. 2016 Dec 5;13(1):205.
Silva CA, Webb K, Andre BG, Marques MA, de Carvalho FM, de Macedo CS, Pinheiro RO, Sarno EN, Pessolani MC, Belisle JT. Type 1 reaction in leprosy patients corresponds with a decrease in pro-resolving and an increase in pro-inflammatory lipid mediators. J Infect Dis. 2016 Dec 8. pii: jiw541.
Martin-Park A, Gomez-Govea MA, Lopez-Monroy B, Treviño-Alvarado VM, Torres-Sepúlveda MD, López-Uriarte GA, Villanueva-Segura OK, Ruiz-Herrera MD, Martinez-Fierro ML, Delgado-Enciso I, Flores-Suárez AE, White GS, Martínez de Villarreal LE, Ponce-Garcia G, Black WC 4th, Rodríguez-Sanchez IP. Profiles of Amino Acids and Acylcarnitines Related with Insecticide Exposure in Culex quinquefasciatus (Say). PLoS One. 2017 Jan 13;12(1):e0169514. doi: 10.1371/journal.pone.0169514.
Dickson LB, Campbell CL, Juneja P, Jiggins FM, Sylla M, Black WC 4th. Exon Enriched Libraries Reveal Large Genic Differences Between Aedes aegypti from Senegal, West Africa and Populations Outside Africa. G3 (Bethesda). 2016 Dec 22. pii: g3.116.036053. doi: 10.1534/g3.116.036053.
Bohn AA, De Morais HA. A Quick Reference on Chloride. Vet Clin North Am Small Anim Pract. 2016 Dec 19. pii: S0195-5616(16)30126-7. doi: 10.1016/j.cvsm.2016.10.008.
Bielefeldt-Ohmann H, Bosco-Lauth A, Hartwig AE, Uddin MJ, Barcelon J, Suen WW, Wang W, Hall RA, Bowen RA. Characterization of non-lethal West Nile Virus (WNV) infection in horses: Subclinical pathology and innate immune response. Microb Pathog. 2016 Dec 21;103:71-79. doi: 10.1016/j.micpath.2016.12.018.
Laurentius LB, Crawford AC, Mulvihill TS, Granger JH, Robinson R, Spencer JS, Chatterjee D, Hanson KE, Porter MD. Importance of specimen pretreatment for the low-level detection of mycobacterial lipoarabinomannan in human serum. Analyst. 2016 Dec 19;142(1):177-185.
Crawford AC, Laurentius LB, Mulvihill TS, Granger JH, Spencer JS, Chatterjee D, Hanson KE, Porter MD. Detection of the tuberculosis antigenic marker mannose-capped lipoarabinomannan in pretreated serum by surface-enhanced Raman scattering. Analyst. 2016 Dec 19;142(1):186-196.
Colbath AC, Dow SW, Phillips JN, McIlwraith CW, Goodrich LR. Autologous and Allogeneic Equine Mesenchymal Stem Cells Exhibit Equivalent Immunomodulatory Properties In Vitro. Stem Cells Dev. 2017 Jan 12. doi: 10.1089/scd.2016.0266.
Alout H, Foy BD. Ivermectin: a complimentary weapon against the spread of malaria? Expert Rev Anti Infect Ther. 2016 Dec 29:1-10. doi: 10.1080/14787210.2017.1271713.
Yang Y, Noviana E, Nguyen MP, Geiss BJ, Dandy DS, Henry CS. Paper-Based Microfluidic Devices: Emerging Themes and Applications. Anal Chem. 2016 Dec 12.
Kirman JR, Henao-Tamayo MI, Agger EM. The Memory Immune Response to Tuberculosis. Microbiol Spectr. 2016 Dec;4(6). doi: 10.1128/microbiolspec.TBTB2-0009-2016.
Angala SK, McNeil MR, Shi L, Joe M, Pham H, Zuberogoitia S, Nigou J, Boot CM, Lowary TL, Gilleron M, Jackson M. Biosynthesis of the methylthioxylose capping motif of lipoarabinomannan in Mycobacterium tuberculosis. ACS Chem Biol. 2017 Jan 11.
Liu J, Bruhn DF, Lee RB, Zheng Z, Janusic T, Scherbakov D, Scherman MS, Boshoff HI, Das S, Rakesh, Waidyarachchi SL, Brewer TA, Gracia B, Yang L, Bollinger J, Robertson GT, Meibohm B, Lenaerts AJ, Ainsa J, Böttger EC, Lee RE. Structure-Activity Relationships of Spectinamide Antituberculosis Agents: A Dissection of Ribosomal Inhibition and Native Efflux Avoidance Contributions. ACS Infect Dis. 2017 Jan 13;3(1):72-88. doi: 10.1021/acsinfecdis.6b00158.
Robertson GT, Scherman MS, Bruhn DF, Liu J, Hastings C, McNeil MR, Butler MM, Bowlin TL, Lee RB, Lee RE, Lenaerts AJ. Spectinamides are effective partner agents for the treatment of tuberculosis in multiple mouse infection models. J Antimicrob Chemother. 2016 Dec 20. pii: dkw467. doi: 10.1093/jac/dkw467.
Brighenti S, Ordway DJ. Regulation of Immunity to Tuberculosis. Microbiol Spectr. 2016 Dec;4(6). doi: 10.1128/microbiolspec.TBTB2-0006-2016.
Cummings JE, Slayden RA. Transient In Vivo Resistance Mechanisms of Burkholderia pseudomallei to Ceftazidime and Molecular Markers for Monitoring Treatment Response. PLoS Negl Trop Dis. 2017 Jan 12;11(1):e0005209. doi: 10.1371/journal.pntd.0005209.
Lee J, Malmberg JL, Wood BA, Hladky S, Troyer R, Roelke M, Cunningham M, McBride R, Vickers W, Boyce W, Boydston E, Serieys L, Riley S, Crooks K, VandeWoude S. Feline immunodeficiency virus cross-species transmission: Implications for emergence of new lentiviral infections. J Virol. 2016 Dec 21. pii: JVI.02134-16. doi: 10.1128/JVI.02134-16.
Wyckoff AC, Kane S, Lockwood K, Seligman J, Michel B, Hill D, Ortega A, Mangalea MR, Telling GC, Miller MW, Vercauteren K, Zabel MD. Clay Components in Soil Dictate Environmental Stability and Bioavailability of Cervid Prions in Mice. Front Microbiol. 2016 Nov 23;7:1885.
Chang L, Fu D, Stenglein MD, Hernandez JA, DeRisi JL, Jacobson ER. Detection and prevalence of boid inclusion body disease in collections of boas and pythons using immunological assays. Vet J. 2016 Dec;218:13-18. doi: 10.1016/j.tvjl.2016.10.006.
Waqas M, Lee HM, Kim J, Telling G, Kim JK, Kim DH, Ryou C. Effect of poly-L-arginine in inhibiting scrapie prion protein of cultured cells. Mol Cell Biochem. 2017 Jan 7. doi: 10.1007/s11010-016-2916-6.
3rd Annual Employee Recognition Event
Check out more fun photos here.
Award Recipients from the MIP Employee Recognition Event
Bev Meyer – MVP Microbiology
Lesley Jones –MVP Pathology
Donna Willard – MVP Foothills
Ashley McGrew – MVP South Campus
Alex Gendernalik –MVP Undergrad Lab Employee
Reyes Murrieta – MVP Graduate Student
Kristen Davenport – MVP DVM Student
Alex Byas – MVP Vet Resident
Julie Moreno –MVP Postdoctoral Fellow
Vicki Cox-Jones –MVP Research Associate or Research Scientist
Jennifer Kahrs -Behind- the-Scenes Playmaker
Sandra Quackenbush – Magnificent Multitasker
Erica Suchman - Outside-the-Box Thinker
Rebekah Kading – Rookie of the Year
Jeff Wilusz - Head Cheerleader
Deryl Keney – Lifetime Achievement
Can’t get enough microbiology? Of course you can’t! A new Microbiology journal club will be held on Wednesdays at 4 PM at Black Bottle Brewing located off of Prospect and College. Contact Anna Fagre for more information.
2nd International Symposium on
Infectious Diseases of Bats Coming to CSU
Can’t wait for Spring Training to start? Well there are other types of bats that you can root for – and they are pretty darn interesting critters from a microbiology perspective. The 2nd International Symposium on Bat Infectious Diseases will be held June 29-July 1 at the University Center for the Arts. For additional information, see http://www.batid.org/ or contact Tony Schountz (firstname.lastname@example.org)
Spring 2017 Rocky Mountain ASM Branch Meeting
The Spring 2017 Rocky Mountain ASM Branch Meeting will be held at AlloSource in Centennial Colorado on April 15th. Be sure to check out the newly updated Rocky Mountain Branch ASM website at https://sites.google.com/site/asmrmb/ for more information.
Mark your Calendar! Rocky Mountain Virology Club- 17th Annual Meeting
The annual Rocky Mountain Virology Club Meeting is scheduled for September 22-24th at Pingree Park. Information on the meeting, including the 9 invited speakers, can be found here.
CMB/BMB/MCIN SPRING POSTER SYMPOSIUM
It is time again for food, fun, drink and a little competition! Please consider presenting a poster for the Annual Cell & Molecular Biology/Molecular, Cellular & Integrative Neurosciences/Biochemistry Poster Symposium.
The Symposium will be held Friday, February 24, 2017 from 3:00 pm – 6:00 pm, judging will start at 3:30 pm.
Submission Deadline is February 10th, 2017 by 5PM!
Deadline: March 20th at 5PM
Attention MIP Faculty: Don’t forget to review the FY17 CRC Call for Proposals and take full advantage of this internal funding competition designed to provide seed money for future external grant proposals.
The American Society for Microbiology is currently accepting applications for their ASM Undergraduate Research Fellowship
The deadline is February 15th!
The Department Seminar Series is in full swing.
The weekly Graduate Student Seminar has also started.
Check out the graduate seminar series schedule here.
Joe Russo Picks up the 7-10 split!
Congratulations to postdoctoral fellow Joe Russo for picking up the nearly impossible 7-10 split at Chippers Lanes on Jan. 23rd in the CSU Monday Night Bowling League...oh yeah and Joe also was lead author on a paper that was published that same week.
All of the Stars Aren't in Hollywood
A few cool shots of various nebulae in the Orion region, along with the Pleiades star cluster.
Michael Scherman has pulled out his trusty telescope and shot these photos on his SV102T apo 102mm refractor with a cooled ASI1600MM camera.
…and we thought microbiologists only used microscopes. Maybe we should start calling Mike our resident ‘Telebiologist’.
“Don’t confuse me with the facts”
- Earl Landgrebe, US Congressman at the Watergate Hearings
Choose your Caption
The Cirque du Soleil show ‘Ovo’recently performed at the Budweiser Events Center in Loveland
1. Haven't seen an egg that big laid around here since that Wilusz guy tried telling a string of jokes in a recent grad class
2. Imagine all of the influenza virus Kristy could grow in that...
3. Egg-Cellent photo, wouldn't you say?
4. Now you can find an egg on MIP webpages in another place other than GrEGG Dean.
5. Submit your own..
The MIP 'Head Cheerleader' recieves his award in his typical understated and highly professional fashion.
1. Channeling the Newton Artwork outside the Micro Bldg, Dr. Wilusz demonstrates that one is truly able to see farther when on the shoulders of giants.
2. Due to rusty techinical skills, many postdocs can claim to 'hold' their PI's hand in the lab every now and then. How many of them can say that they had to hold their PI’s feet?
3. Somebody might have had one too many glasses of 'cheer' at the reception...
Microbiology-Themed Trinkets Steal the Show at the 2nd Floor Prion Research Center Christmas Tree Ornament Contest
Members of the Mathiason and Hoover Laboratories enjoy the smell of fresh pine.
1st place: This ZIKV-infected creature was found buzzing the Christmas tree
2nd place: The Gingerbread Bead Man brought 'mixers' to the celebration
3rd place: So… this is really what the inside of a TSE-infected brain looks like… caffeine vacuoles.
21st Century Cures Act Passes Congress In December Congress authorized spending $4.7 billion new dollars to fund several large research initiatives, including the Cancer Moonshot, regenerative medicine and brain research. To learn more about these research opportunities see here .
New Font Guidelines for NIH Grants
New Grant Awards
John Belisle, "BMAC CSU Core Facility Mass Spectrometry Services," HHS-CDC-Centers for Disease Control. "Biology and Biosignatures of Anti-Tuberculosis Treatment Response," HHS-NIH-NIAID-Allergy and Infect Diseases.
William Black, "Assessing the Genetic Basis of Arboviral Salivary Gland Escape Barriers in Aedes aegypti," HHS-NIH-NIAID-Allergy and Infect Diseases.
Brian Foy, "Zika Virus Urogenital Tropism, Pathogenesis and Sexual Transmission," HHS-NIH-NIAID-Allergy and Infect Diseases.
Ed Hoover, "Biomedical Research Training for Veterinarians," HHS-NIH-National Institutes of Health.
Anne Lenaerts, "TB Drug Accelerator: TB Mouse in vivo Models," Global Alliance for Tuberculosis Drug Development.
Kenneth Olson, "Task Order Request C03: "Efficacy Study for Nootkatone as Insecticidal Agent against Mosquitoes Harboring Arboviruses (including ZIKV)," HHS-NIH-NIAID-Allergy and Infect Diseases.
Greg Robertson, "Broad Institute-CSoft TB Therapeutic Effort," The Broad Institute.
John Spencer, "Immunological and Molecular Signatures of Leprosy: Tracking Transmission and Disease Progression in Brazil," The New York Community Trust.
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