Vol. 12 | No. 2
The only thing constant is change……..
Since our recently appointed Managing Editor, Copy Editor, News Editor, Opinion Editor, Feature Editor, Sports Editor, Photo/Graphics Editor, and Advertising Manager named Dan Champion has run off to re-kindle his middle school teaching career, we searched long and hard for someone to fill his shoes. We are pleased to announce that the glass slipper fit on the foot of Collette Hageman (nee DeWitt) who will serve as our new MIPnews production editor. Jeff Wilusz will remain in his position as Editor-in-Chief. So please submit all newsworthy stories and pictures to Collette Hageman or Jeff Wilusz.
Good Riddance Dan! Click Here to see Dan's going away party...Along with his new body-builder Physique.
Collette got hitched!
Collette DeWitt is now Collette Hageman!
Andrea's baby shower
Andrea stopped by with her adorable daughter, Emma Grace. Click the picture below to see the baby shower photos.
MIP Publications July 2015
Roode SC, Rotroff D, Avery AC, Suter SE, Bienzle D, Schiffman JD, Motsinger-Reif A, Breen M. Genome-wide assessment of recurrent genomic imbalances in canine leukemia identifies evolutionarily conserved regions for subtype differentiation. Chromosome Res. 2015 Jun 3. [Epub ahead of print]
Irwin SM, Driver E, Lyon E, Schrupp C, Ryan G, Gonzalez-Juarrero M, Basaraba RJ, Nuermberger EL, Lenaerts AJ. Presence of multiple lesion types with vastly different microenvironments in C3HeB/FeJ mice following aerosol infection with Mycobacterium tuberculosis. Dis Model Mech. 2015 Jun 1;8(6):591-602.
Meyers JI, Gray M, Kuklinski W, Johnson LB, Snow CD, Black WC 4th, Partin KM, Foy BD. Characterization of the target of ivermectin, the glutamate-gated chloride channel, from Anopheles gambiae. J Exp Biol. 2015 May 15;218(Pt 10):1478-86.
Cooley RB, Smith TJ, Leung W, Tierney V, Borlee BR, O'Toole GA, Sondermann H. Cyclic di-GMP-regulated periplasmic proteolysis of a Pseudomonas aeruginosa type Vb secretion system substrate. J Bacteriol. 2015 Jun 22. pii: JB.00369-15. [Epub ahead of print]
Hasan NA, Davidson RM, de Moura VC, Garcia BJ, Reynolds PR, Epperson LE, Farias-Hesson E, DeGroote MA, Jackson M, Strong M. Draft Genome Sequence of Mycobacterium chelonae Type Strain ATCC 35752. Genome Announc. 2015 May 28;3(3). pii: e00536-15. doi: 10.1128/genomeA.00536-15.
Wheat WH, Dhouib R, Angala SK, Larrouy-Maumus G, Dobos K, Nigou J, Spencer JS, Jackson M. The presence of a galactosamine substituent on the arabinogalactan of Mycobacterium tuberculosis abrogates full maturation of human peripheral blood monocyte-derived dendritic cells and increases secretion of IL-10. Tuberculosis (Edinb). 2015 Jul;95(4):476-89. doi: 10.1016/j.tube.2015.04.002.
Chaccour CJ, Rabinovich NR, Slater H, Canavati SE, Bousema T, Lacerda M, Ter Kuile F, Drakeley C, Bassat Q, Foy BD, Kobylinski K. Establishment of the Ivermectin Research for Malaria Elimination Network: updating the research agenda. Malar J. 2015 Jun 11;14(1):243. doi: 10.1186/s12936-015-0691-6.
Meyers JI, Gray M, Foy BD. Mosquitocidal properties of IgG targeting the glutamate-gated chloride channel in three mosquito disease vectors (Diptera: Culicidae). J Exp Biol. 2015 May 15;218(Pt 10):1487-95.
Bullard KM, Gullberg RC, Soltani E, Steel JJ, Geiss BJ, Keenan SM. Murine Efficacy and Pharmacokinetic Evaluation of the Flaviviral NS5 Capping Enzyme 2-Thioxothiazolidin-4-One Inhibitor BG-323. PLoS One. 2015 Jun 15;10(6):e0130083. doi: 10.1371/journal.pone.0130083.
Sweeney NL, Hanson AM, Mukherjee S, Ndjomou J, Geiss BJ, Steel JJ, Frankowski KJ, Li K, Schoenen FJ, Frick DN. Benzothiazole and Pyrrolone Flavivirus Inhibitors Targeting the Viral Helicase. ACS Infect Dis. 2015 Mar 13;1(3):140-148.
Via LE, Savic R, Weiner DM, Zimmerman MD, Prideaux B, Irwin SM, Lyon E, O'Brien P, Gopal P, Eum S, Lee M, Lanoix JP, Dutta NK, Shim T, Cho JS, Kim W, Karakousis PC, Lenaerts A, Nuermberger E, Barry CE 3rd, Dartois V. Host-Mediated Bioactivation of Pyrazinamide: Implications for Efficacy, Resistance, and Therapeutic Alternatives. ACS Infect Dis. 2015 May 8;1(5):203-214.
Lanoix JP, Lenaerts AJ, Nuermberger EL. Heterogeneous disease progression and treatment response in a C3HeB/FeJ mouse model of tuberculosis. Dis Model Mech. 2015 Jun 1;8(6):603-10.
Lyons MA, Lenaerts AJ. Computational pharmacokinetics/pharmacodynamics of rifampin in a mouse tuberculosis infection model. J Pharmacokinet Pharmacodyn. 2015 May 31. [Epub ahead of print]
Gumbo T, Lenaerts AJ, Hanna D, Romero K, Nuermberger E. Nonclinical models for antituberculosis drug development: a landscape analysis. J Infect Dis. 2015 Jun 15;211 Suppl 3:S83-95. doi: 10.1093/infdis/jiv183.
Kuzmina TA, Hernández-Orts JS, Lyons ET, Spraker TR, Kornyushyn VV, Kuchta R. The cestode community in northern fur seals (Callorhinus ursinus) on St. Paul Island, Alaska. Int J Parasitol Parasites Wildl. 2015 May 8;4(2):256-63. doi: 10.1016/j.ijppaw.2015.04.007.
Telling G. Neurodegeneration: Evolved protection against human prions. Nature. 2015 Jun 10. doi: 10.1038/nature14534.
Pritzkow S, Morales R, Moda F, Khan U, Telling GC, Hoover E, Soto C. Grass plants bind, retain, uptake, and transport infectious prions. Cell Rep. 2015 May 26;11(8):1168-75. doi: 10.1016/j.celrep.2015.04.036.
Wilusz J. Circular RNA and Splicing: Skip Happens. J Mol Biol. 2015 May 30. pii: S0022-2836(15)00317-4. doi: 10.1016/j.jmb.2015.05.019
The National Trust has bought the Great Orme
What plans might the National Trust have for Orme (besides applying more spray-on tan to his face to match his torso….)? Check it out Here
On May 15, 2015 the rain held off long enough to allow the Dobos Lab to spend a day at The Harmony House of Fort Collins, which is part of CASA of Larimer County (http://casalarimer.com/). The historical Ziegler family farmhouse is used for visits between children and adults in need of a safe and comfortable environment.
Last November, the Dobos Lab spent a day of service doing a deep clean on the house and some Fall yardwork that needed and they knew that they wanted to come back in the Spring and serve again. The lab had specific goals in mind and knew what supplies they needed, so Keri Wright went out and personally petitioned local businesses for supplies. Businesses were eager to help them out, and they received over $660 in donations and gift cards! With the donations and gift cards, they gathered supplies including treated wood and screws, flowers and flower pots, bushes, sand, soil, weed cover, and weed killer. After gathering all of the supplies, they spent the day cleaning up the yard, weeding, planting, and fixing up a badly deteriorated porch.
The lab wants to acknowledge the local businesses who were generous in our endeavor: Gulley Greenhouse, Fort Collins Nursery, Walmart on N. Denver in Loveland, Walmart on 65th St. in Loveland, Home Depot on Magnolia, Ace Hardware of Windsor, Lowe's in Loveland, Lowe's in Fort Collins, Fossil Creek Nursery, Hersh Trees, and Home Depot on JFK Parkway. In addition, they are very grateful for the help of Karen’s husband Chris, and his friend Rob who spent their time helping them in the project by planning, destructing, and rebuilding the porch.
Fighting Leprosy One School at a Time
Ever wonder what motivates John Spencer to get up out of bed and go to work every morning? I guess you can sum it up in one word – Leprosy. Eighty percent of all leprosy cases occur in India, Indonesia, and Brazil. John Spencer works closely with a team of researchers and clinicians led by Dr. Claudio Salgado in Pará, Brazil in the Amazon region. Since 2009, the team has made repeated site visits to a dozen communities in Pará. John and colleagues visit schools to diagnose new cases in children, and then visit those children’s households to try to find the index case so that treatment of all of those diagnosed will stop the spread of disease. Read Spence’s full ‘faculty profile’ that was prepared by CVMBS here.
Resident Reception 2015
MIP Inspires Young Minds
On June 24th Phillida Charley, Jennifer McLean, Erica Suchman, and Ashley McGrew inspired some of the young students at the UTE-Conference to study Microbiology. View photos here.
TB or Non-TB? That is the question (and the latter is the answer)
The 1st European Symposium on Non-tuberculosis Mycobacterium occurred from June 24th-27th 2015 in Borstel, Germany. Invited chairs and speakers were Dr. Pat Brennan, Dr. Delphi Chatterjee, Dr. Torsten Eckstein and Dr. Diane Ordway. The picture is take in from of the Manor House, Research Center Borstel, Germany.
You’re 2014-15 CSU parking permit exipred on Friday, July 31 and new academic year permits are now required to park on campus. You can renew your permit online http://parking.colostate.edu/pages/PermitLink.aspx
Choose your Caption
1. Do you still believe that scientists weren’t part of the ‘cool kids’ growing up?
The Pizza Bandit... or Bandits strike again!!!!!!
MIP Emeritus Prof Can Shoot with the Best of ‘Em
New Grant Awards
Anne Lenaerts, "TB Drug Accelerator: TB Mouse in vivo Models - Planning Grant", Gates Foundation (Bill and Melinda).
Dean Crick, "Unraveling the Origin of Pyrazinamide's Synergy With Other Anti-TB Drugst", HHS-NIH-NIAID-Allergy & Infect Diseases.
Kristen Davenport, "Characterizing the Role of Protein Interactions in Prion Disease Species Barriers", HHS-NIH-National Institutes of Health.
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