Dr. Gerald Callahan was chosen as the 2006 Eddy Teacher because of his extraordinary achievements in teaching, research and scholarship, including contributions to the University Honors Program. He has had much success as a writer and teacher bridging science and the humanities (for an example see Callahan GN. First self. Emerg Infect Dis Vol 11, Issue 2. 2005 ).

The award honors the legacy of Willard O. Eddy, CSU professor from 1937 to 1993, a great champion of the liberal arts and sciences and founder of the University Honors Program.

Read the CSU announcement.

Two NIH awards will provide $1.1 million to continue screening for effective drugs to combat tuberculosis and $6.7 million to develop new medications for drug-resistant strains of tuberculosis. The research team, headed by Ian Orme and Anne Lenaerts, has identified several new compounds that are highly effective against tuberculosis strains that do respond to drugs. This funding will allow the team to test the compounds against drug resistant strains.
Read the complete CSU Article

Research led by Edward Hoover and spearheaded by Candace Mathiason shows for the first time that chronic wasting disease may spread through saliva and blood of infected deer, which poses new possibilities that the disease may spread by blood-sucking insects or social contact between animals. The study also reinforcesthe notion that no tissue from an infected animal can be considered free of prions, the disease-causing agent. The research was released in the Oct. 6 edition of .
Read the complete CSU Article

Hana Van Campen received the Colorado Veterinary Medical Association's Outstanding Faculty Award for 2006. This award recognizes a Colorado State University faculty member who has provided unselfish assistance to practitioners as a clinician, is a proficient and capable teacher, and/or has made significant contributions to continuing education.

Zach Freeman, Robert Sons, and Beth Stallman are all involved in programs sponsored by the Office of the President.

Zach is one of just thirteen participants in the Presidential Internship Program, and is the first Presidential Intern from our College. Zach is working on a project to further enhance the connections between our university and international agencies, with the goal of using some of the research and teaching performed at Colorado State to help prevent and control infectious diseases in Africa.

Robert Sons and Beth Stallman are both participants in the President's Leadership Program, a fourteen-credit experience that encompasses all levels of leadership development. In addition, Robert is the Finance Officer for ASCSU and Beth is the president of the Microbiology Student Association.

Sarah Garcia is a participant in the McNair Scholars Program. This program helps prepare students who are interested in a career in research and/or college teaching. Sarah is gaining research experience working in the laboratory of Dr. Karen Dobos.

Danielle Cogswell is a recipient of the Beckman Scholarship, which is awarded to students who demonstrate potential in research. Danielle is working in the research laboratory of Dr. Julia Inamine and Dr. Torsten Eckstein.

Undergraduate Research Fellowships

This year the American Society for Microbiology awarded 43 highly competitive Undergraduate Research Fellowships nationally. Of those 43 awards three were awarded to MIP Undergraduates Tess Brodie, Robert Sons, and Megan Van Dyken. This is quite an honor for the recipients as well as for the department. Congratulations!

Lisa Woolhiser defended her Masters thesis on August 18 entitled, "Modeling Persistent Mycobacterium tuberculosis infection in mice"

Tshidi Tsibane defended her Doctoral dissertation on August 22 entitled, "MCF Pathogenesis: Studies on the replication and tropism of OvHV-2 in peripheral blood mononuclear cells of ruminants"

MIP Publications Late August-early October 2006

• Bishop JV, Mejia JS, Perez de Leon AA, Tabachnick WJ, Titus RG. Salivary Gland Extracts of Culicoides sonorensis Inhibit Murine Lymphocyte Proliferation and No Production by Macrophages. Am J Trop Med Hyg., 75(3), 2006, pp. 532-536.
• Nelson KG, Bishop JV, Ryan RO, Titus RG. Nanodisk-Associated Amphotericin B Clears Leishmania major Cutaneous Infection in Susceptible BALB/c Mice. Antimicrobial Agents and Chemotherapy, Apr. 2006, p1238-1244.
• Webb C, Bedwell C, Guth A, Avery P, Dow S. Use of flow cytometry and monochlorobimane to quantitate intracellular glutathione concentrations in feline leukocytes. Vet Immunol Immunopathol. 2006 Aug 15;112(3-4):129-40
• Basaraba RJ, Smith EE, Shanley CA, Orme IM. Pulmonary lymphatics are primary sites of Mycobacterium tuberculosis infection in guinea pigs infected by aerosol. Infect Immun. 2006 Sep;74(9):5397-401.
• Rojas RE, Thomas JJ, Gehring AJ, Hill PJ, Belisle JT, Harding CV, Boom WH. Phosphatidylinositol Mannoside from Mycobacterium tuberculosis Binds {alpha}5beta1 Integrin (VLA-5) on CD4+ T Cells and Induces Adhesion to Fibronectin. J Immunol. 2006 Sep 1;177(5):2959-68.
• Mikusova K, Belanova M, Kordulakova J, Honda K, McNeil MR, Mahapatra S, Crick DC, Brennan PJ. Identification of a novel galactosyl transferase involved in biosynthesis of the mycobacterial cell wall. J Bacteriol. 2006 Sep;188(18):6592-8.
• Calisher CH, Childs JE, Field HE, Holmes KV, Schountz T. Bats: important reservoir hosts of emerging viruses. Clin Microbiol Rev. 2006 Jul;19(3):531-45. Review.
• Shi L, Berg S, Lee A, Spencer JS, Zhang J, Vissa V, McNeil MR, Khoo KH, Chatterjee D. The carboxy terminus of EmbC from Mycobacterium smegmatis mediates chain length extension of the arabinan in lipoarabinomannan. J Biol Chem. 2006 Jul 14;281(28):19512-26. Epub 2006 May 10.
• Schultheiss PC. Histologic features and clinical outcomes of melanomas of lip, haired skin, and nail bed locations of dogs. J Vet Diagn Invest. 2006 Jul;18(4):422-5
• Cleveland SM, Salman MD, Van Campen H. Assessment of a bovine viral diarrhea virus antigen capture ELISA and a microtiter virus isolation ELISA using pooled ear notch and serum samples. J Vet Diagn Invest. 2006 Jul;18(4):395-8
• Kurosu, M.; Crick, D. C. A Novel Strategy for Oligopeptide Synthesis Using a Polymer-supported Ammonium Fluoride. Tetrahedron Lett. 2006, 47, 5325.
• Junqueira-Kipnis AP, Basaraba RJ, Gruppo V, Palanisamy G, Turner OC, Hsu T, Jacobs WR Jr, Fulton SA, Reba SM, Boom WH, Orme IM. Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon-gamma. Immunology. 2006 Oct;119(2):224-31
• Kurosu, M.; Dey, S. S.; Crick, D, C. Efficient Synthesis of Tertiary Amines from Secondary Amines. Tetrahedron Lett. 2006, 47, 4871.
• Kurosu, M.; Mowers, W. A. Samll-Molecule Microarrays: Development of Novel Linkers and an Efficient Detection Method for Bound Proteins. Bioorganic & Medicinal Chemistry Letters 2006, 16, 3392.
• Burnside KL, Ryan JT, Bielefeldt-Ohmann H, Gregory Bruce A, Thouless ME, Tsai CC, Rose TM. RFHVMn ORF73 is structurally related to the KSHV ORF73 latency-associated nuclear antigen (LANA) and is expressed in retroperitoneal fibromatosis (RF) tumor cells. Virology. 2006 Oct 10;354(1):103-15.
• Grzenia DL, Carlson JO, Czermak P, Han B, Specht RK, Wickramasinghe SR. Purification of Densonucleosis Virus by Tangential Flow Ultrafiltration. Biotechnol Prog. 2006 Oct 6;22(5):1346-1353.
• Kurosu, M. Cr-waste Free Catalytic Carbonyl Addition Reactions with Polymer-immobilized CrF2 Complex. Tetrahedron Lett. 2006, 47, 3395.
• Kurosu, M.; Kitagawa, I. Ganglioside GM3 Derivatives with Truncated Ceramide Moiety: Facial Synthesis and Inhibitiory Activity Against KB Cell Growth. J. Carbohydrate.Chem. 2006, 25, 427.
• Grubor B, Meyerholz DK, Lazic T, DeMacedo MM, Derscheid RJ, Hostetter JM, Gallup JM, DeMartini JC, Ackermann MR. Regulation of surfactant protein and defensin mRNA expression in cultured ovine type II pneumocytes by all-trans retinoic acid and VEGF. Int J Exp Pathol. 2006 Oct;87(5):393-403.
• Mathes M, Jordan M, Dow S. Evaluation of liposomal clodronate in experimental spontaneous autoimmune hemolytic anemia in dogs. Exp Hematol. 2006 Oct;34(10):1393-402.
• Mathiason CK, Powers JG, Dahmes SJ, Osborn DA, Miller KV, Warren RJ, Mason GL, Hays SA, Hayes-Klug J, Seelig DM, Wild MA, Wolfe LL, Spraker TR, Miller MW, Sigurdson CJ, Telling GC, Hoover EA. Infectious prions in the saliva and blood of deer with chronic wasting disease. Science. 2006 Oct 6;314(5796):133-6.
• Kumar A, Chua KL, Schweizer HP. Method for Regulated Expression of Single-Copy Efflux Pump Genes in a Surrogate Pseudomonas aeruginosa Strain: Identification of the BpeEF-OprC Chloramphenicol and Trimethoprim Efflux Pump of Burkholderia pseudomallei 1026b. Antimicrob Agents Chemother. 2006 Oct;50(10):3460-3.
• Anderson JR, Mukherjee D, Muthukumaraswamy K, Moraes KC, Wilusz CJ, Wilusz J. Sequence-specific RNA binding mediated by the RNase PH domain of components of the exosome. RNA. 2006 Oct;12(10):1810-6.

Barb Powers will be the next President of the American Association of Veterinary Laboratory Diagnosticians.

• Mary Ann DeGroote, MD , will join MIP on November 1^st in Ian Orme's Laboratory, where she will play an active role in the collaborative research efforts for TB drug development. Dr. DeGroote comes to us from the Department of Medicine at the University of Colorado Health Sciences Center.

• Debra Kamstock, DVM, DACVP, started her appointment with MIP on October 1^st providing diagnostic service within the Veterinary Diagnostic Laboratory. Dr. Kamstock received her residency training at CSUVDL and is completing her PhD research in Steven Dow's Laboratory.

Construction has begun on the Microbiology Student Study Lounge! Last year, CSU students voted for an increase in fees to provide a pool of dollars for construction projects. High on the students list of priorities was a study area located on the southern part of main campus. An addition on the northwest side of the Microbiology Building will provide for this need.

Highlights of the event include a reception, comments by MIP's Andre Ptitsyn, and a demonstration of recently AEP-purchased hardware and software.

The Colloquium is designed to benefit investigators with research activities that could be applied to Zoonotic disease but have not received Zoonotic disease funding in the past, as well as researchers with established Zoonotic disease programs.
For updates check the Vice President for Research website.

Northwest corner of the RBL Complex with stucco and paint.

The southeast corner of the RBL showing the animal holding loading dock.

Interior corridor on the North side of the RBL by the BSL3 labs.

Connecting corridor between Discovery and RBL attic mechanical areas.

Thanks for the photos Jerry!

	Connie Heighes, Accounting Tech in Microbiology
	Melody Orso, Accounting Tech in Microbiology
	Chad Workman, Accounting Tech in Microbiology

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Colorado Combined Campaign donation packets were recently distributed to everyone in MIP. Please take a moment to review this important program and consider contributing.

"I'll bet living in a nudist colony takes all the fun out of Halloween." ~Author Unknown

Mon	Tue	Wed	Thur	Fri
2	3 Graduate Seminar 12-noon	4 Microscopy Seminar	5 Faculty Seminar 4pm	6
9 Faculty Seminar 4pm	10 Graduate Seminar 12-noon	11 Microscopy Seminar	12	13
16 Faculty Seminar 4pm	17 Graduate Seminar 12-noon	18 Microscopy Seminar	19	20
23 Faculty Seminar 4pm	24 Graduate Seminar 12-noon	25 Microscopy Seminar	26	27
30 Faculty Seminar 4pm	31

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