December 2014
Vol. 11 | No. 6
Congratulations to University Distinguished Professor, Ian Orme, for being named a Fellow of the prestigious Amercian Association for the Advancement of Science (AAAS). Orme was recoginzed by the AAAS for his groundbreaking work on vaccines and drugs for tuberculosis. This year the AAAS named 401 new Fellows for their scientifically or socially distinguished efforts to advance science or its applications. New Fellows will be presented with an official certificate and a gold and blue rosette pin on Feb. 14 during the 2015 AAAS Annual Meeting in San Jose, Calif. For the full story please visit the Source website. Way to go Ian! Greetings! I recently joined the MIP department and am excited to return to Colorado State University (CSU) to work alongside researchers and diagnosticians within the university and department. I am assuming responsibility for the CSU Veterinary Diagnostic Lab’s virology and sample receiving sections and plan to build upon the foundation of my ongoing research on bluetongue virus infection of livestock, to improve our current understanding of arboviral disease dynamics within a changing world, especially with respect to urbanization, climate change, and the domestic-wildlife interface. After I received my DVM degree from the University of Georgia, I completed a microbiology residency at CSU. My training in the residency program, under the mentorship of Dr. Hana Van Campen, formed my initial understanding of classical and molecular virology techniques. She also initiated my first journey into research during a field investigation of bluetongue in Colorado and this experience allowed me to start developing research questions and creating novel diagnostics. Throughout my PhD and postdoctoral training at the University of California, Davis, I have continued to adapt these techniques in the laboratory and field working within a diverse set of disciplines (virology, epidemiology, entomology). I’m excited to continue these projects and be involved in new adventures at CSU. When I’m not working, it’s not unusual to see me running, swimming, or in the Yoga studio and I’m looking forward to re-exploring Colorado’s hiking trails. MIP Graduate Students who received their Degrees on December 19...
Erin Borland, MS MIP Undergraduate Students who received their B.S. Degrees on December 20...
Brianna Baca Congratulations to Lauren Radakovich for winning the ASVCP Young Investigator Award for her platform presentation entitled “Reticulocyte hemoglobin content (CHr) does not differentiate true from functional iron deficiency in dogs” at the ACVP meeting in Atlanta. Way to go Lauren! Congratulations to Elijah Edmondson for having two manuscripts selected as Vet Path editor’s choice articles for the year! “Editor's Choice Collection in Veterinary Pathology highlights the journal's most noteworthy manuscripts of the year.” Nicely done Elijah! "Pathologic and Cardiovascular Characterization of Pheochromocytoma-Associated Cardiomyopathy in Dogs" has been selected for the Editor's Choice Collection (Companion Animals category). “Prognostic Significance of Histologic Features in Canine Renal Cell Carcinomas: 70 Nephrectomies” was selected for Editor’s Choice Collection (Surgical Pathology category). Evaluation of ivermectin mass drug administration for malaria transmission control across different West African environments Haoues Alout, Ben Krajacich, Jacob Meyers, Nathan Grubaugh, Doug Brackney, Kevin Kobylinski, Joseph Diclaro II, Fatorma Bolay, Lawrence Fakoli, Abdoulaye Diabate, Roch Dabire, Roland Bougma and Brian Foy Malaria Journal 13: 417 (2014) When there’s malaria in the area, Brian Foy ain’t a happy camper. The good news on the malaria front is that we’ve been able to cut global mortality rates by 47% since 2000. The bad news is that the drugs and insecticides that fueled this success are becoming less and less effective due to the rise of resistant parasites and mosquito vectors. The disease also still takes an enormous toll on the human population (~584,000 deaths in 2013, mostly among African children). Thus Brian is passionate about finding a way to truly ‘Foy-al’ this pathogen once and for all….. MIP Publications August 2014 Orme IM, Basaraba RJ. J. The formation of the granuloma in tuberculosis infect Semin Immunol. 2014 Oct 22;26(6):601-609. Kim HJ, Brennan PJ, Heaslip D, Udey MC, Modlin RL, Belisle JT. . Carbohydrate Dependent Binding of Langerin to SodC, a Cell Wall Glycoprotein of Mycobacterium lep J Bacteriol. 2014 Nov 24. pii: JB.02080-14 Saavedra-Rodriguez K, Beaty M, Lozano-Fuentes S, Denham S, Garcia-Rejon J, Reyes-Solis G, Machain-Williams C, Loroño-Pino MA, Flores-Suarez A, Ponce-Garcia G, Beaty B, Eisen L, Black WC 4th. Local Evolution of Pyrethroid Resistance Offsets Gene Flow among Aedes aegypti Collections in Yucatan State, Me Am J Trop Med Hyg. 2014 Nov 4. pii: 14-0277 Reyes-Solis Gdel C, Saavedra-Rodriguez K, Suarez AF, Black WC 4th. QTL mapping of genome regions controlling temephos resistance in larvae of the mosquito Aedes aegy PLoS Negl Trop Dis. 2014 Oct 16;8(10):e3177. doi: 10.1371/journal.pntd.0003177 Dickson LB, Sanchez-Vargas I, Sylla M, Fleming K, Black WC 4th. Vector competence in West African Aedes aegypti Is Flavivirus species and genotype dependent. PLoS Negl Trop Dis. 2014 Oct 2;8(10):e3153. doi: 10.1371/journal.pntd.0003153. Vap L, Bohn AA. Hematology of Camelids Vet Clin North Am Exot Anim Pract. 2015;18(1):41-49. doi: 10.1016/j.cvex.2014.09.010. Seabaugh KA, Goodrich LR, Bohn AA, Morley PS, Hendrickson DA. A comparison of peritoneal fluid values in mares following bilateral laparoscopic ovariectomy using a vessel sealing and dividing device versus placement of two ligating loops. Vet J. 2014 Nov;202(2):297-302. Blair CD, Olson KE. Mosquito immune responses to arbovirus infections. Curr Opin Insect Sci. 2014 Sep 1;3:22-29. Daffé M, Crick DC, Jackson M. Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids. Microbiol Spectr. 2014;2(4). pii: 14. Krajacich BJ, Slade JR, Mulligan RF, LaBrecque B, Alout H, Grubaugh ND, Meyers JI, Fakoli LS, Bolay FK, Brackney DE, Burton TA, Seaman JA, Diclaro JW 2nd, Dabiré RK, Foy BD. Sampling Host-Seeking Anthropophilic Mosquito Vectors in West Africa: Comparisons of An Active Human-Baited Tent-Trap against Gold Standard Methods. Am J Trop Med Hyg. 2014 Nov 24. pii: 14-0303. Alout H, Krajacich BJ, Meyers JI, Grubaugh ND, Brackney DE, Kobylinski KC, Diclaro JW 2nd, Bolay FK, Fakoli LS, Diabaté A, Dabiré RK, Bougma RW, Foy BD. Evaluation of ivermectin mass drug administration for malaria transmission control across different West African environments. Malar J. 2014 Nov 3;13:417. doi: 10.1186/1475-2875-13-417. Henao-Tamayo M, Obregón-Henao A, Creissen E, Shanley C, Orme I, Ordway DJ. Differential expression of BCG vaccine derived efficacy in C3Heb/FeJ and C3H/HeOuJ mice exposed to a clinical strain of Mycobacterium tuberculosis. Clin Vaccine Immunol. 2014 Nov 12. pii: CVI.00466-14 Haley NJ, Hoover EA. Chronic Wasting Disease of Cervids: Current Knowledge and Future Perspectives. Annu Rev Anim Biosci. 2014 Oct 2. Allison AB, Kohler DJ, Ortega A, Hoover EA, Grove DM, Holmes EC, Parrish CR. Host-specific parvovirus evolution in nature is recapitulated by in vitro adaptation to different carnivore species. PLoS Pathog. 2014 Nov 6;10(11):e1004475. doi: 10.1371/journal.ppat.1004475 Henderson DM, Davenport KA, Haley NJ, Denkers ND, Mathiason CK, Hoover EA Jr. Quantitative Assessment of Prion Infectivity in Tissues and Body Fluids by RT-QuIC. J Gen Virol. 2014 Oct 10. pii: vir.0.069906-0. doi: 10.1099/vir.0.069906-0. Shukla S, Richardson ET, Athman JJ, Shi L, Wearsch PA, McDonald D, Banaei N, Boom WH, Jackson M, Harding CV. Mycobacterium tuberculosis Lipoprotein LprG Binds Lipoarabinomannan and Determines Its Cell Envelope Localization to Control Phagolysosomal Fusion. PLoS Pathog. 2014 Oct 30;10(10):e1004471. doi: 10.1371/journal.ppat.1004471. Aiyaz M, Bipin C, Pantulwar V, Mugasimangalam R, Shanley CA, Ordway DJ, Orme IM. Whole genome response in guinea pigs infected with the high virulence strain Mycobacterium tuberculosis TT372. Tuberculosis (Edinb). 2014 Oct 13. pii: S1472-9792(14)20491-4. doi: 10.1016/j.tube.2014.10.001 Williams MJ, Shanley CA, Zilavy A, Peixoto B, Manca C, Kaplan G, Orme IM, Mizrahi V, Kana BD. bis-Molybdopterin guanine dinucleotide is required for persistence of Mycobacterium tuberculosis in guinea pigs. Infect Immun. 2014 Nov 17. pii: IAI.02722-14. Correa AF, Bailão AM, Bastos IM, Orme IM, Soares CM, Kipnis A, Santana JM, Junqueira-Kipnis AP. The Endothelin System Has a Significant Role in the Pathogenesis and Progression of Mycobacterium tuberculosis Infection. Infect Immun. 2014 Dec;82(12):5154-65. doi: 10.1128/IAI.02304-14. Burgess BA, Weller CB, Pabilonia KL, Bolte DS, Van Metre DC, Morley PS. Detection of Different Serotypes of Salmonella enterica in Experimentally Inoculated Equine Fecal Samples by Commercially Available Rapid Tests. J Vet Intern Med. 2014 Nov;28(6):1853-9. Duncan C, Dickerson B, Pabilonia K, Miller A, Gelatt T. Prevalence of Coxiella burnetii and Brucella spp. in tissues from subsistence harvested northern fur seals ( Callorhinus ursinus ) of St. Paul Island, Alaska. Acta Vet Scand. 2014 Oct 1;56(1):67. Fox KA, Rouse NM, Huyvaert KP, Griffin KA, Killion HJ, Jennings-Gaines J, Edwards WH, Quackenbush SL, Miller MW. BIGHORN SHEEP (OVIS CANADENSIS) SINUS TUMORS ARE ASSOCIATED WITH COINFECTIONS BY POTENTIALLY PATHOGENIC BACTERIA IN THE UPPER RESPIRATORY TRACT. J Wildl Dis. 2014 Nov 6. [Epub ahead of print] Kuhn JH, Dürrwald R, Bào Y, Briese T, Carbone K, Clawson AN, deRisi JL, Garten W, Jahrling PB, Kolodziejek J, Rubbenstroth D, Schwemmle M, Stenglein M, Tomonaga K, Weissenböck H, Nowotny N. Taxonomic reorganization of the family Bornaviridae. Arch Virol. 2014 Dec 2. [Epub ahead of print] Giovarelli M, Bucci G, Ramos A, Bordo D, Wilusz CJ, Chen CY, Puppo M, Briata P, Gherzi R. H19 long noncoding RNA controls the mRNA decay promoting function of KSRP. Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):E5023-8. doi: 10.1073/pnas.1415098111 Jalkanen AL, Wilusz J. Stem cell RNA epigenetics: m(6)arking your territory. Cell Stem Cell. 2014 Dec 4;15(6):669-70. Wilusz JE, Wilusz J. Nonsense-mediated RNA decay: at the 'cutting edge' of regulated snoRNA production. Genes Dev. 2014 Nov 15;28(22):2447-9. |
SAVE THE DATE! The 16th Annual CVMBS Research Day will be held January 31, 2015 at the Hilton Fort Collins. Student scientists conducting clinical and basic studies in all CVMBS departments are encouraged to participate. Students must submit research abstracts by 2 p.m. Monday, Jan. 5. Authors should indicate a preference for poster or oral presentations. For more information please visit the CVMBS Research Day webpage or contact Aimee Oke or Dr. Brad Borlee.
The American Society for Microbiology is currently accepting applications for their ASM Undergraduate Research Fellowship The deadline is February 1st! Judges are needed for the 60th anniversary of the Colorado Science and Engineering Fair, which will attract hundreds of talented students in sixth through 12th grades to the CSU campus. These students will present research in the fields of science, technology, engineering and mathematics in an effort to continue developing their interests and ideas. To register please visit Colorado State Science Fair and for additional information please contact Erica Suchman. Several MIP Professors and Graduate Students (Hannah Romo and Danielle Adney) have been participating in a joint effort with Pateros Creek Brewery to make science less scary and learning about it more enjoyable. The result is Science on Tap, a once a month event where local scientists share information and knowledge about "in the news science" with the general public. Pateros Creek provides happy hour priced beer to all attendees. The first event was held in November and the topic of discussion was "Ebola: Separating fact from fiction". The panel consisted of Drs. Mark Zabel, Greg Ebel, Jeff Wilusz and Alan Schenkel. It was standing room only! The topic of discussion for the December event was “The Flu: The gift that keeps on giving” and the panel of experts included Drs. Richard Bowen, Gabriele Landolt, Bin Lu and Kristy Pabilonia. The Colorado Combined Campaign is one opportunity for CSU faculty and staff to support their favorite community charities via payroll deduction. If you are interested in participating you will need to do so by December 31. You can either donate online or with the paper pledge form you should have received in the mail. For more information, visit the Colorado Combined Campaign website. This holiday season MIP adopted three families in need through the Salvation Army “Angels Among us” program. A total of ten children benefited from the generosity of MIP faculty, staff and students. Thank you to everyone who participated, your kindness is very much appreciated! A very special thank you to Carol Wilusz for organizing the effort and to Dan Champion, Tach Costello and Ida Tieman for assisting with the collection of gifts. Happy Holidays everyone! On December 5th the DMIP Employee Recognition Event was held in the Lory Student Center Ballroom. Employees gathered for dinner, drinks and dancing. The Absolutes, a local band provided a wonderful mix of soul, funk, blues, motown and R & B that kept the crowd moving. Awards ranging from Legendary Lab Assistant to Best Beard were also given out. Thank you to all who participated and to Dr. Randy Basaraba and Dan Champion for organizing the event. Check out the photos! On Thursday, November 21st the department gathered for the annual Thanksgiving Potluck. A variety of Thanksgiving favorites, including turkey, mashed potatoes, stuffing and an assortment of delicious desserts were consumed. A good time was had by all. Check out the photos! MIP'ers once again filled the department hallways with characters of all types. Check out some of this year's costumes in the MIP Halloween 2014 Photo Gallery. Hello Friends and Colleagues, |
New Grant Awards Brian Geiss, "A High-Throughput Screen for Antiviral Inhibitors of the Alphavirus RNA Capping Enzyme", NIH-NIAID Brian Foy, "Dry-to-Rainy Season Repeated Ivermectin MDA and ITN Distribution for Integrated Control of NTDs and Malaria", Gates Foundation DECEMBER
2014
JANUARY
2015
Do you have NEWS or PICTURES you would like to share? Send In your ideas or newsworthy items. Contributions make the Newsletter better! |
MIP Newsletter Volume 11, Issue 6, December 2014
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