September 2014
Vol. 11 | No. 4

Spotlight

AIDL Group Paper Gets Top Honor From the Royal Entomological Society

Royal Entomological Society Logo

Ken Olson

We are proud to announce that the paper:

"Transgene-mediated suppression of the RNA interference pathway in Aedes aegypti interferes with gene silencing and enhances Sindbis virus and dengue virus type 2 replication" by CCH Khoo, JB Doty, MS Heersink, KE Olson, and AWE Franz, Insect Molecular Biology (2013), 22(1), 104-114

was awarded the 2014 Award for Best Paper published in Insect Molecular Biology by the Royal Entomological Society. Kudos to Ken, Alexander et al!


MIP Faculty Conversion

Three more MIP faculty are no longer as ‘Special’ as they used to be…Congratulations to the following faculty on their conversion from 'special appointment' to 'regular appointment' tenure track positions.

Chad FrankChad Frank
Assistant Professor
Diane Ordway Diane Ordway
Assistant Professor
Carol WiluszCarol Wilusz
Associate Professor

MIP Special Appointment

Marcella Henao-Tamayo Seba Mahapatra

Drs. Marcela Henao-Tamayo and Seba Mahapatra have received Special Appointment Assistant Professor positions in the MIP department. Congratulations Marcela and Seba!


Everyday Hero Award Donna Willard photo Donna Willard, Assistant Manager for the Foothills Campus, has been recognized with an Everyday Hero Award by the Classified Personnel Council. Audrey Oberlin nominated Donna for her positive attitude and strong work ethic. "She epitomizes what I believe is an everyday hero. Hard working, conscientious, goal driven and completely out of the lime light. She does the best job because it is the right thing to do and no other outcome is acceptable." Congratulations Donna!

…..Look for Donna in a supporting role if we ever make that ‘Guardians of the MIP Galaxy’ movie.


Gerald Callahan textbook cover

Gerald Callahan

How do you follow up the ‘Lousy Sex’ he gave us in 2013? Dr. Gerald Callahan has now co-authored a new textbook, Basic Veterinary Immunology, that was published by the University Press of Colorado in Boulder. The text offers a solid background in the essentials of immunology within the context of veterinary medicine. Hence it should fill a large resource gap in this important area of the veterinary curriculum. Way to go Gerry!


West Nile Virus in the Fort Mosquito

Dr. Chet Moore's expertise in West Nile Virus was recently featured in the Fort Colllins Coloradoan. I guess you could say that MIP definitely adds the ‘say it’ part to the ‘say it, don’t spray it’ debate…Check out the great picture of Chet and read the full article.


PMF Global Recognition

CSU's Proteomic and Metabolomic Facility (PMF) has earned global recognition as a "Center of Innovation"! The award comes from Waters, a global supplier of analytical laboratory instruments, in recognition of PMF’s cutting-edge analytical techniques. A key part of the recognized successes that drove this high honor is the development and implementation of something called ‘MRM-MS technology’ by MIP investigators Nicole Kruh-Garcia and Karen Dobos in collaboration with Jessica Prenni and her PMF staff. For more on this technology, also check out this issue’s MIPublication of the Month or Today@ColoradoState. Congratulations to the PMF as well as Nicole and Karen for this impressive recognition!


In the News...

Smith Owl Photo

MIP Professor Emeritus Ralph Smith's photograph of two baby screech owls was chosen as the "Photo of the Week" in the Fort Collins Coloradoan. Great Picture Ralph!


pub highlight

Detection of Mycobacterium tuberculosis peptides in the exosomes of patients with active and latent M. tuberculosis infection using MRM-MS

Nicole Kruh-Garcia, Lisa Wolfe, Lelia Chaisson, William Worodria, Payam Nahid, Jeff Schorey, J. Lucian Davis and Karen Dobos

PLoS ONE, July 2014, Volume 9, e103811

“Acid Fast” may make for a great name for an MIP road running team, but it leaves something to be desired as a diagnostic test for tuberculosis. The old ‘spit and smear’ approach is only ~50% effective in diagnosing M. tuberculosis infections. While batting .500 in baseball will get you into the Hall of Fame on the first ballot, getting it right only 50% of the time is a rather ‘2014 Rockies-esque’ performance in the game of diagnostics. Commercially available serology-based diagnostics for the disease are even worse. With almost 9 million cases of M. tb infection per year and tuberculosis second only to HIV/AIDS in human deaths caused by an infectious agent, we need to do better - Period.

In this publication, Nicole, Lisa, Karen and their worldwide team of collaborators lay a very interesting foundation for identifying a ‘biosignature’ of sorts in human serum that can be used to answer the Shakespearean question of whether a person has ‘TB or not TB’. Their hypothesis relied on three foundational things. First, they are experts in a form of mass spectrometry called LC-MS/MS which is extraordinarily sensitive for peptides down to the high attomolar range (I was going to ask my dentist what an attomolar is, but I remembered my personal policy to keep the inane jokes to myself when someone is holding a drill to my face…..). Second, building upon work that they initiated in 2010, they picked 76 peptides from 33 M. tb proteins that they thought they would have a good chance of being detecting in infected human serum samples. Finally, they exploited a cool way to remove the large background of human proteins in serum that would create a huge amount of noise in their assay. They accomplished this by isolating small membrane bound vesicles called exosomes from the serum samples. These exosomes often bud off of cells affected by diseases and thus may very well contain the majority of M. tb proteins in the blood.

They tested their hypothesis using a blinded set of 59 exosome preparations from individual patient sera and got some very encouraging results. 95% of TB patients had at least one M. tb peptide marker in their serum, with an average of 8 detectable peptides per patient. Using a panel of only 9 peptide signatures, they could diagnose 90% of the patients. Increasing the panel size to a mere 10 peptides they could diagnose all but two of the TB samples tested. The bottom line: ~90% is MUCH better than 50% (whether we’re talking about a grade on the first MIP300 exam or the world of TB diagnosis….).

So why did we chose this paper as our coveted MIPublication of the Month©? Frankly, just re-read the last paragraph. This is an extremely promising biomarker approach that addresses the very important problem of inefficient TB diagnosis. In closing, we’d like to suggest one small change to the study. How about changing the name of the technique from ‘Multiple Reaction Monitoring Mass Spectrometry’ (or MRM-MS) to ‘Multiple Reaction Lc Mass Spectrometry’ so that the acronym would be an MIP-friendly ‘MRL-MS’?????


MIP Publications August 2014

Veselinovic M, Yang KH, LeCureux J, Sykes C, Remling-Mulder L, Kashuba AD, Akkina R. HIV pre-exposure prophylaxis: Mucosal tissue drug distribution of RT inhibitor Tenofovir and entry inhibitor Maraviroc in a humanized mouse model. Virology. 2014 Aug 5;464-465C:253-263.

Eisen L, García-Rejón JE, Gómez-Carro S, Nájera Vázquez Mdel R, Keefe TJ, Beaty BJ, Loroño-Pino MA. Temporal correlations between mosquito-based dengue virus surveillance measures or indoor mosquito abundance and dengue case numbers in Mérida City, México. J Med Entomol. 2014 Jul;51(4):885-90.

Loroño-Pino MA, Chan-Dzul YN, Zapata-Gil R, Carrillo-Solís C, Uitz-Mena A, García-Rejón JE, Keefe TJ, Beaty BJ, Eisen L. Household use of insecticide consumer products in a dengue-endemic area in México. Trop Med Int Health. 2014 Jul 17. doi: 10.1111/tmi.12364.

Shi L, Ryan GJ, Bhamidi S, Troudt J, Amin A, Izzo A, Lenaerts AJ, McNeil MR, Belisle JT, Crick DC, Chatterjee D. Isolation and purification of Mycobacterium tuberculosis from H37Rv infected guinea pig lungs. Tuberculosis (Edinb). 2014 Jun 30. pii: S1472-9792(14)20479-3. doi: 10.1016/j.tube.2014.05.003

Li W, Upadhyay A, Fontes FL, North EJ, Wang Y, Crans DC, Grzegorzewicz AE, Jones V, Franzblau SG, Lee RE, Crick DC, Jackson M. Novel Insights into the Mechanism of Inhibition of MmpL3, a Target of Multiple Pharmacophores in Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2014 Aug 18. pii: AAC.03229-14.

Kruh-Garcia NA, Wolfe LM, Chaisson LH, Worodria WO, Nahid P, Schorey JS, Davis JL, Dobos KM. Detection of Mycobacterium tuberculosis Peptides in the Exosomes of Patients with Active and Latent M. tuberculosis Infection Using MRM-MS. PLoS One. 2014 Jul 31;9(7):e103811. doi: 10.1371/journal.pone.0103811.

Sun Z, Kang Y, Norris MH, Troyer RM, Son MS, Schweizer HP, Dow SW, Hoang TT. Blocking Phosphatidylcholine Utilization in Pseudomonas aeruginosa, via Mutagenesis of Fatty Acid, Glycerol and Choline Degradation Pathways, Confirms the Importance of This Nutrient Source In Vivo. PLoS One. 2014 Jul 28;9(7):e103778. doi: 10.1371/journal.pone.0103778.

Campbell CL, Smith DR, Sanchez-Vargas I, Zhang B, Shi PY, Ebel GD. A positively selected mutation in the WNV 2K peptide confers resistance to superinfection exclusion in vivo. Virology. 2014 Aug 4;464-465C:228-232. doi: 10.1016/j.virol.2014.07.009

Lozano-Fuentes S, Welsh-Rodriguez C, Monaghan AJ, Steinhoff DF, Ochoa-Martinez C, Tapia-Santos B, Hayden MH, Eisen L. Intra-annual changes in abundance of Aedes (Stegomyia) aegypti and Aedes (Ochlerotatus) epactius (Diptera: Culicidae) in high-elevation communities in Mexico. J Med Entomol. 2014 Jul;51(4):742-51.

Kobylinski KC, Alout H, Foy BD, Clements A, Adisakwattana P, Swierczewski BE, Richardson JH. Rationale for the Coadministration of Albendazole and Ivermectin to Humans for Malaria Parasite Transmission Control. Am J Trop Med Hyg. 2014 Jul 28. pii: 14-0187.

Belardinelli JM, Larrouy-Maumus G, Jones V, de Carvalho LP, McNeil MR, Jackson M. Biosynthesis and Translocation of Unsulfated Acyltrehaloses in Mycobacterium tuberculosis. J Biol Chem. 2014 Aug 14. pii: jbc.M114.581199.

Jackson M. The Mycobacterial Cell Envelope-Lipids. Cold Spring Harb Perspect Med. 2014 Aug 7. pii: a021105. doi: 10.1101/cshperspect.a021105.

De Groote MA, Gibbs S, de Moura VC, Burgess W, Richardson K, Kasperbauer S, Madinger N, Jackson M. Analysis of a panel of rapidly growing mycobacteria for resistance to aldehyde-based disinfectants. Am J Infect Control. 2014 Aug;42(8):932-4. doi: 10.1016/j.ajic.2014.05.014.

Meyer M, Freihofer P, Scherman M, Teague J, Lenaerts A, Böttger EC. In-vivo Efficacy of Apramycin in Murine Infection Models. Antimicrob Agents Chemother. 2014 Aug 18. pii: AAC.03239-14.

Moore AR, Allender MC, MacNeill AL. Effects of ranavirus infection of red-eared sliders (Trachemys scripta elegans) on plasma proteins. J Zoo Wildl Med. 2014 Jun;45(2):298-305.

Willingham K, McNulty E, Anderson K, Hayes-Klug J, Nalls A, Mathiason C. Milk collection methods for mice and reeves' muntjac deer. J Vis Exp. 2014 Jul 19;(89). doi: 10.3791/51007.

Angers R, Christiansen J, Nalls AV, Kang HE, Hunter N, Hoover E, Mathiason CK, Sheetz M, Telling GC. Structural effects of PrP polymorphisms on intra- and interspecies prion transmission. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11169-74. doi: 10.1073/pnas.1404739111. Epub 2014 Jul 17.

Weishaar KM, Edmondson EF, Thamm DH, Olver CS. Malignant mesenchymoma with widespread metastasis including bone marrow involvement in a dog. Vet Clin Pathol. 2014 Jul 30. doi: 10.1111/vcp.12180

Henao-Tamayo M, Ordway DJ, Orme IM. Memory T cell subsets in tuberculosis: What should we be targeting? Tuberculosis (Edinb). 2014 Jun 17. pii: S1472-9792(14)20474-4. doi: 10.1016/j.tube.2014.05.001.

Amsellem PM, Selmic LE, Wypij JM, Bacon NJ, Culp WT, Ehrhart NP, Powers BE, Stryhn H, Farese JP. Appendicular osteosarcoma in small-breed dogs: 51 cases (1986-2011). J Am Vet Med Assoc. 2014 Jul 15;245(2):203-10.

Root JJ, Shriner SA, Bentler KT, Gidlewski T, Mooers NL, Spraker TR, VanDalen KK, Sullivan HJ, Franklin AB. Shedding of a low pathogenic avian influenza virus in a common synanthropic mammal - the cottontail rabbit. PLoS One. 2014 Aug 11;9(8):e102513. doi: 10.1371/journal.pone.0102513.

Beatty JA, Troyer RM, Carver S, Barrs VR, Espinasse F, Conradi O, Stutzman-Rodriguez K, Chan CC, Tasker S, Lappin MR, VandeWoude S. Felis catus gammaherpesvirus 1; a widely endemic potential pathogen of domestic cats. Virology. 2014 Jul;460-461:100-7.


Happenings

Charlie Calisher Book Signing

Please join Dr. Charlie Calisher for a discussion of his book "Lifting the Impenetrable Veil: From Yellow Fever to Ebola Hemorrhagic Fever and SARS" and get your copy signed!


Roger Jaenke Memoriam

Dr. Roger Jaenke, a valued member of the Pathology Department from 1969 to 1993 passed away on August 21, 2014. A memorial service and open house will be held on September 20 at 10 am at Foothills Unitarian Church, 1815 Yorktown Ave, Fort Collins, CO.


RMVC Annual Meeting Announcement

Please visit the Rocky Mountain Virology Club website for additional information and to register for the meeting.


Saturday, October 25, 2014
9:00 am

Worner Campus Center:
Gaylord Hall
Colorado College
Colorado Springs, CO 80903

An ASM Distinguished Lecture will be given by Dr. Stephen Lory (Harvard Medical School) and the Keynote Address will be by Dr. Phoebe Lostroh (Colorado College). Registration is free for all students, and lunch is free for all attendees who preregister for the meeting. Student and postdoc travel and presentation awards are also available. This meeting is an excellent opportunity for students and postdocs to gain valuable presentation experience and to help build your resume. For more information and registration information, click here.


Welcome New Graduate Students
Enrique DosterEnrique Doster
Enrique is originally from south Texas and graduated from Auburn University in Alabama with a degree in Animal Sciences. His past research was in fresh water ecology and equine reproduction. He is looking forward to exploring the exciting research opportunities at CSU as he develops his research career. Outside of research, Enrique spends most of his time outdoors with his dog, Moose. If you see Enrique around, please say hello. He is always happy to strike up a conversation.
Dilara KiranDilara Kiran
Dilara is a new student in the combined degree DVM/PhD program.She is from Blacksburg, Virginia and recently graduated from the College of William & Mary in Williamsburg with a B.S. in Biology. Dilara's research interests lie in the areas of infectious diseases and bacterial pathogenesis. At CSU, Dilara hopes to join the Mycobacterial Research Laboratories. In her spare time, Dilara enjoys playing the French horn and hopes to find a group at CSU or in Fort Collins to perform with.
Kaitlyn MiedemaKaitlyn Miedema
Kaitlyn is originally from Green Bay, WI (Go Pack Go!) and completed her B.S. in Biology at the University of Wisconsin - La Crosse this past May. She is interested in studying the immunology and transmission of infectious diseases. When she is not studying she likes to go hiking, rock climbing and boating.
Reyes MurrietaReyes Murrieta
Reyes received his undergraduate degree in Microbiology from the University of Arizona. He is interested in Infectious Disease research, specifically Vector-born pathogens and thier interaction within resevoir and host. He enjoys hiking, rock climbing and bicycling in his free time.
Nora Jean NealonNora Jean Nealon
Nora Jean is also in the combined degree DVM/PhD program. She earned her B.S. in 2013 from Rutgers University, where she majored in Veterinary Science, Nutrition and Biology, with minors in Endocrinology and Companion Animal Science. Her passion for animals, science and teaching grew from an eclectic mix of jobs which include conducting research projects, working in small animal hospitals, taking care of exotics at a country park, working for Residence Life, leading SAT classes, tutoring chemistry and even teaching a class on music of the 1960's. In her spare time, Nora Jean enjoys baking, listening to music, long-distance running, rescuing turtles and spending time with her sister. She is a self-proclaimed "Westie-Lover", and takes pride in telling others all about the antics of Sir Winston, her mischievous three year old West Highland White Terrier.
Kat Stutzman-RodriguezKat Stutzman-Rodriguez
Kat just finished her second year in the DVM program here at CSU and received a NIH T32 grant to take a year off of vet school for research and to complete an MS. She is excited to be working in Sue VandeWoude's lab on development of a serologic assay for the newly discovered Feline gammaherpesvirus 1.

Welcome New Residents
Allison VilanderAllison Vilander
Anatomic Pathology

Allison is from the beautiful state of Washington and received her D.V.M. from Washington State University in 2010. During Vet school she discovered a love for pathology. She is also interested in infectious disease and animal models of human disease. In her free time she enjoys hiking, backpacking, snowboarding, and adventuring with her husband, pug, and two cats.
Jennifer HouleJennifer Houle
Comparitive Medicine

Jennifer grew up on a farm outside of Portland, Oregon where she raised sheep, rode horses and participated in 4-H. She received her D.V.M. from Washington State University. Jennifer was fortunate to work on a variety of research projects which allowed her to cultivate a strong interest in research in conjunction with clinical veterinary medicine, ultimately leading her to the field of lab animal and comparative medicine. Her professional interests include metabolic disease, neurology, and biomarkers of disease. In her free time, Jennifer and her husband have been enjoying the bounty of outdoor activities Colorado has to offer—running, hiking, backpacking, and more!
Emily RoutEmily Rout
Clinical Pathology

Emily grew up in Pennington, New Jersey and moved to Colorado to attend Vet school at CSU. She receivd her D.V.M. in 2013. Her research interests include biomarkers for regenerative anemia in horse and canine lymphoma and plans to continue studying lymphoma during her residency. She enjoys swimming, golf, skiing, cooking and running with her husband and two dogs, Addie and Henry.
Dipu Mohan KumarDipu Mohan Kumar
Microbiology Resident

Originally from India, Dipu moved to the United States after completing vet school and receiving a masters in Diagnostic Microbiology. His research interests include infectious diseases and microbial pathogens. In his spare time Dipu enjoys exploring Fort Collins, the mountains, new restaurants, yoga, cooking, baking, spending time with friends and playing with his roommate's dog.
Erin LeeErin Lee
Comparative Medicine

Erin and her husband recently moved to Colorado from College Station, Texas where she received her D.V.M. Her research interests include animal models of infectious diseases, medical devices and pre-clinical studies. In her free time she enjoys writing and is currently working on a fantasy-adventure novel that she hopes to publish one day. She is a volunteer firefighter and medical first responder and also enjoys running, cycling and playing computer / tabletop games.
Laura Hoon-HanksLaura Hoon-Hanks
Anatomic Pathology

Originally from Montana, Laura received her D.V.M. from CSU in 2014. Her research interests are focused on infectious disease pathology with an emphasis in vector-borne and zoonotic diseases. In her free time she loves to mountian bike, hike, backpack, white-water raft, rock climb, snowboard & trail run. She also enjoys a good brewery tour, BBQ, happy hour and movies at the drive-in theater.

Bon Voyage

Two MIP Faculty members will be leaving this Fall. Dr. Lars Eisen has accepted a position with the CDC and Dr. Herbert Schweizer will assume the positions of Preeminence Professor in the Department of Molecular Genetics and Microbiology, College of Medicine, and Director of Emerging Pathogens Institute BSL 3 facilities at the University of Florida. Best of luck Lars and Herbert!

Several staffing changes are happening in the Ebel Laboratory too. First, Dr. Doug Brackney, a senior Research Scientist will be leaving in October to start an independent research position at the Connecticut Agricultural Experimental Station. Dr. Abhishek Prasad defended his thesis in June and will be departing for a postdoc at UTMB, studying Ebola in Dr. Alexander Buckreyev's Lab. Lastly, Benjamin Dodd, a Research Associate will be moving to Boulder. Congratulations Doug, Abhi and Ben and best of luck on your future endeavors!


Colorado Rockies Logo Rockies Game 2014

Thanks to the MIP Graduate Student Organization for arranging a trip to Coors Field on Thursday, August 14th to watch the Rockies play the Reds. Tickets were only $10 and carpooling and designated drivers were provided. The best part...Rockies WON!


Pikes Peak Marathon Logo

Jennifer Malmberg

Congratulations to MIP grad student and resident, Jennifer Malmberg for finishing 5th out of 182 in the overall female division of the Pikes Peak Marathon. You rock Jennifer!


Summer Adventures

Global Virus Network Logo

In June Dr. Timothy Quinn Crawford, a post doc from the Akkina lab, and Dr. Aaron T. Phillips, a post doc from the Olson lab, traveled to Baltimore MD to take part in the first annual Global Virus Network (GVN) Short Course in Medical Virology. Quinn was awarded one of three Reinhard Kurth Fellowships to attend the course. They spent a week learning from some of the world's top virologist on the state of medical virology across the globe. Lectures were held at the University of MD, Johns Hopkins and the NIH, covering a wide range of topics from basic virology to vaccine development and public policy. They even visited the White House and met with officials from the Office of Science Technology and Policy.

Quinn Crawford at GVN Course

Quinn Crawford with Ab Osterhaus, Head of the Dept. of Viroscience at the Erasmus Institute in Rotterdam and Bob Gallo, Director of the Institute of Human Virology at the University of MD.


Barry Beaty at GVN Course

MIP's very own Barry Beaty was an instructor for the course. He is seen here leading a round table discussion.


Mini Takes the States Logo

Keri Wright MINI rally

Keri Wright and her MINI Cooper.

Keri Wright from the Dobos laboratory hit the road this summer to take part in the MINI Takes the States rally (MTTS). The rally is a consumer based loyalty event that started in San Francisco on July 26 and ended in Boston on August 10. MINI owners from all over the US rally across the country stopping only to sleep and eat. Keri drove from Grand Junction, CO to Dallas, TX stopping in Albuquerque, Lubbock and Austin along the way. Check out the other photos from her trip!


Wild West Relay Logo Jason Cummings and Lesely Jones at the WWR

Jason Cummings and Lesley Jones were part of a 12 person relay team that ran from Fort Collins to Steamboat Springs August 1-2. They finished in 31 hours and couldn't have done it without their amazing Team Captain, Kristine Bennett.


Got Parking?

Parking Services has transitioned to virtual permits and license plate recognition technology to enforce the parking regulations. This requires all permit holders to register the license plate of any vehicle they may be driving to campus. You may register multiple vehicles to your permit, but only one vehicle can park on campus at a time.

More information can be found at the Parking and Transportation website.


MIP Bits

Quote of the Month

"I accept it. Money well spent"
  ~ Peyton Manning (and numerous MIP 2014 grant awardees)



Camels

Dan Champion recently served as Fire Marshall during the yearly Fire Drill of the Microbiology Facility

    Alternative Captions:
  1. Looks like Dan might be making a guest appearance on ‘Orange is the New Black’ this Fall
  2. 2014 ‘Rocking the Vest’ Champion
  3. Remember to drop your extra change in the cleverly decorated collection receptacles for the MIP ‘New Vest Fest’
  4. Not sure if the alarm in the building goes off only when there’s smoke/fire – or if Dan wearing this vest is sufficient to cause a mass evacuation.
  5. Submit your own

MIPuzzle
Questions for MIPuzzle #93
MIPuzzle #93 Answers
MIPuzzle #93


Polished Nail Art
Nail Art

Selene Garcia Luna created this nail design for the ASV meeting.


NIH Happenings

  • An Additional Paperwork Requirement for Trainees in your Annual Report

    Note that for progress reports submitted after October 1st, you must report on individual development plans for your student and postdoc trainees (for all grants, not just training grants). For more info, check out: http://grants.nih.gov/grants/guide/notice-files/NOT-OD-14-113.html

  • ACS IRG Seed Grants available to young investigators through the CO Comprehensive Cancer Center

    This is a $30K grant opportunity for early stage faculty without substantial external funding. The deadline is October 27th. For more info, check out the website.


New Grant Awards

bulletAnne Lenaerts, "Novel Spectinamide Antibiotics for the Treatment of MDR/XDR Tuberculosis", Microbiotix, Inc.

bulletLars Eisen, "Testing of Mosquito Pools for West Nile Virus, City of Fort Collins, 2014", City of Fort Collins

bulletMary Jackson, "MmpL3 as a Target for Novel Anti-TB Drugs", Potts Memorial Foundation

bulletRamesh Akkina, "Multi-Species Mechanisms of Drug Bio-Distribution in HIV Tissue Reservoirs", UNC-University of North Carolina

bulletDoug Brackney, "Quantification and Purification of Large Quantities of Powassan Virus and Deer Tick Virus RNA", Battelle Memorial Institute

bulletDoug Brackney, "Vector BioSensor: A Novel Approach for Enhancing Biological Sample Acquisition for Biosurveillance Efforts", DOD-ARMY-WRAIR

bulletCarol Brennan "Novel Approaches for Development of Monoclonal Antibodies Against Encephalitic Alphaviruses with Enhanced Therapeutics", DOD-DTRA

bulletGregg Dean "Oral Induction of Mucosal and Systemic Antibodies Against HIV-1 gp41 MPER", NIH-NIAID

bulletMary Ann DeGroote "Optimization and Lead Selection of Novel Antimycobacterial Agents", Crestone, Inc

bulletMercedes Gonzalez-Juarrero "siRNA-gold Nanoparticles Host Targeted Therapy for Tuberculosis", NIH-NIAID

bulletAngelo Izzo "Advanced Small Animal Models for the Testing of Candidate Therapeutic and Preventive", NIH-NIAID

bulletAngelo Izzo "Testing of Mutant Mycobacteria in Established Advanced Small Animal Models",NIH-NIAID

bulletAnne Lenaerts "Mouse Models for the Early Stage of Lead Drug Candidates against Mycobacterial Species", NIH-NIAID

bulletAnne Lenaerts "Novel Protein Synthesis Inhibitors for the Treatment of MDR Tuberculosis", St. Jude Medical, Inc.

bulletKaren Dobos "Mycobacterium spp. Research Reagent Replenishment ", ATCC

bulletRamesh Akkina "Unmasking the Latent HIV Reservoir Using Humanized Mice", AmFAR

bulletRandall Basaraba "Therapeutic Restoration of Metabolic Homeostasis during Active TB", NIH-NIAID

bulletSandra Quackenbush "Molecular Biology Services for Wildlife Disease Diagnostics", Colorado Division of Parks and Wildlife


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MIP-GSO Workshop



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 Charlie Calisher visting Chaco Canyon

Charlie Calisher visited Chaco Canyon National Historical Park in New Mexico. The Hopi place name for Chaco Canyon is “Yupkoyvi”. We’re not sure what the Hopi call Charlie, but will be sure to let you know ASAP.


Don't Forget Employee Recognition Donation

Remember to contribute any loose change to the DMIPWSFERE (Department of Microbiology Immunology and Pathology Winter Strategic Forum and Employee Recognition Event) fund. Collection receptacles can be found in Departmental offices!


Marcela Henao Tamayo at the Trudeau Institute

Marcela Henao Tamayo vistited the Trudeau Institute where she met Edward Livingstone Trudeau himself. “He was a bit blue and didn’t say much” she reported.


Welcome Hike 2014

Several Graduate Students enjoyed the Welcome Hike to Arthur's Rock.


Do you have NEWS or PICTURES you would like to share?

Send In your ideas or newsworthy items. Contributions make the Newsletter better!

MIP Newsletter Volume 11, Issue 4, September 2014
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