Vol. 10 | No. 4
Congratulations to Dr. John Belisle for receiving the 2013 Scholarship Impact Award, bestowed by the Office of the Vice President for Research. The Scholarship Impact Award is the University's highest award for accomplishment in research, recognizing faculty whose scholarship has had a major impact nationally and/or internationally.
Read the full CSU Press Release.
Congratulations to Cathy Griffin, Pathology Office Manager, for receiving the CVMBS 2013 Outstanding Employee Service Award. Cathy was nominated by CVMBS faculty and staff for her exemplary service to the College.
Congratulations to Dr. Brad Borlee for receiving the Boettcher Webb-Waring Early Investigator Biomedical Research Award. The program supports early career investigators whose research has a direct impact on human health. The grant is intended to fund translational research that advances a discovery closer to clinical applications and that will improve the understanding, treatment and prevention of human disease. Awardees carry the prestigious title of "Boettcher Investigator".
Each semester, the MIP faculty recognize an outstanding graduating senior for academic excellence and/or service to the department or community. Ryan Knodle is the recipient of this award for the May 2013 graduating class.
Ryan certainly has an outstanding academic record. He graduated with a GPA that is just shy of a perfect 4.0; all A and A+ grades except for two B grades earned early in his college career. Ryan earned these high marks completing not only the rigorous curriculum required for a degree in Microbiology, but also the requirements for a minor in Biomedical Sciences and completion of the Honors Scholars Program, This accomplishment is all the more impressive considering that Ryan also worked part-time at the CSU Recreation Center, where his work day often began very early in the morning (as in O-dark-thirty early!) and was followed by a long day of classes.
Obviously, Ryan was very busy with school and his job, but he somehow still found the time, motivation, and energy to work in the research laboratory of Dr. Angelo Izzo (Ryan was awarded High Honors for a poster presentation of his data at the CSU Research Symposium) AND to volunteer at the Medical Center of the Rockies AND to be an active member of the Microbiology Student Association (vice-president last year and president this year) AND to serve as a student representative on the University Facility Fees Board (in that role Ryan was very helpful in securing funding for a proposed addition to the Anatomy/Zoology Building). Ryan was also instrumental in the launch of the CSU Journal of Undergraduate Research, one of only a handful f of peer-reviewed undergraduate publications in the country, and he has been both a co-editor of and a contributor to the journal.
Ryan has been able do all this, and do it well, because he is intelligent, has a strong work-ethic, enjoys working with people (and people like working with him), knows how to manage his time and prioritize tasks, handles stress well, and can apparently get by on little or no sleep. These characteristics will serve Ryan very well in the next chapter of his life, which begins this fall, as a medical student at the University of Illinois-Chicago.
Congratulations, Ryan, and best of luck in your future endeavors!
Congratulations to Stephanie Moon for being selected as a School of Global Environmental Sustainability (SoGES) 2013-14 Global Sustainability Leadership Fellowship. The SoGES Global Sustainability Leadership Fellows program cultivates future innovators and thought leaders capable of effectively communicating not only with peers but also with the public.
Congratulations to the following faculty on their upcoming promotion and/or tenure actions which become effective July:
Congratulations to the following students who will be completing their Veterinary Residency Program this year:
A reception was held on Thursday, June 20 from 3:00-4:30 in the Pathology Glover Gallery. View the Reception Photos.
MIP Undergraduate Students who received their B.S. Degrees Spring 2013
*Candidate for graduation with distinction: Cum Laude
MIP Graduate Students who received their MS or PhD Degrees Spring 2013
Mike Barnhart, MS (CMB)
Check out photos of the MIP'ers at the Graduate School Graduation Ceremony.
Congratulations to Alexandra Harvey, student trainee in the Akkina Laboratory, for receiving the CSU Student of the Year Award from the President's Leadership Program.
Nunya Chotiwan, BS, MS Program, defended her dissertation entitled, "Molecular Determinants of Dengue Virus Type-2 Critical for Early Events in Antibody-Dependent Enhancement of Infection" on May 29. Her advisors are Dr. Carol Blair and Dr. Claire Kinney.
Linnell Randall, BS, MS Program, defended her dissertation entitled, "Sub-cellular Localization of the PenA β-lactamase in Burkholderia pseudomallei" on May 31. Her advisor is Dr. Herbert Schweizer.
Kelly Walton, DVM, MS Program, defended her dissertation entitled, "Murine Models of Staphylococcus aureus Biofilm Infections and Therapeutic Protein A Vaccination" on June 6. Her advisors are Dr. Lon Kendall and Dr. Steve Dow.
Marta Lishnevsky, BS, Phd Program, defended her dissertation entitled, “Mechanisms of Pulmonary Fibrosis in PECAM-1 Deficient FVB/n Mice” on June 24. Her advisor is Dr. Alan Schenkel.
Alana Garner, DVM, MS Program, defended her dissertation entitled, ""Correlation of Mast Cell Tumor Aggressiveness With Degree of Cutaneous Mucinosis in Chinese Shar-Pei Dogs" on June 26. Her advisor is Dr. Anne Avery.
Rebecca Crew, BS, MS Program, defended her dissertation entitled, "Bioinformatic Identification and Functional Characterization of Cytokinetic Regulators in MTB" on June 26. Her advisor is Dr. Ric Slayden.
Filaria taxideae in Striped Skunks (Mephitis mephitis) of Colorado, USA, and Commonly Associated Filarial Dermatitis
Karen Fox, Laura Martin, Laurie Baeten, Brett Webb, Ivy LeVan, Lora Ballweber and Lisa Wolfe
Journal of Wildlife Diseases, Vol. 49: 738-740 (July 2013)
When one of those cute little black & white striped skunks that live in the Fort Collins area greets you on the trail, ain’t it hard not to want to bend down and scratch him/her playfully behind the ear? Well new work from Karen et al reported this month in the Journal of Wildlife Diseases might make you think twice about stroking that furry little darling. It turns out that 8 of 51 (or ~16%) of striped skunks (officially called Mephitis mephitis [which by the way is Latin for Basaraba’s socks…]) have their skin infected with a small filarial worm. The adult worm lays eggs in between the layers of the skin. These eggs cause a variety of skin irritations that help move them out to the surface to allow the parasite to spread. Half of the infected skunks showed clear clinical signs of the ailment such as skin irritations, crusting over and the occasional pleasant to behold ulceration. So unless you want to risk a filarial infection (not to mention fun stuff like rabies or getting a not-so- attractive ‘eau de skunk’ perfuming…..), we’d recommend keeping your distance from these critters.
So why did we choose this study as our coveted MIPublication of the month? First, there’s been very little work on the parasitology of the skunk (go figure, eh?), particularly in this area. Thus the study fills a major knowledge gap. Second, the work was apparently done as an off shoot of a simple survey of area wildlife for rabies infection. Thus it demonstrates the resourcefulness and dedication of the Dlab group to take the time and get the most information possible from valuable animal samples. Finally, we here at MIPnews can simply smell great science from a mile away – and this one definitely had a scent that we couldn’t resist……
MIP Publications June 2013
Engel S, Randall EK, Cuddon PA, Webb BT, Aboellail TA. IMAGING DIAGNOSIS: MULTIPLE CARTILAGINOUS EXOSTOSES AND CALCINOSIS CIRCUMSCRIPTA OCCURRING SIMULTANEOUSLY IN THE CERVICAL SPINE OF A DOG. Vet Radiol Ultrasound. 2013 Jun 14. doi: 10.1111/vru.12066.
Akkina R. Human immune responses and potential for vaccine assessment in humanized mice. Curr Opin Immunol. 2013 Apr 26. doi:pii: S0952-7915(13)00062-9. 10.1016/j.coi.2013.03.009.
Fox KA, Martin LE, Baeten LA, Webb BT, Levan IK, Ballweber LR, Wolfe LL. Filaria taxideae in Striped Skunks (Mephitis mephitis) of Colorado, USA, and Commonly Associated Filarial Dermatitis. J Wildl Dis. 2013 Jul;49(3):738-40. doi: 10.7589/2012-12-303.
Skyberg JA, Rollins MF, Samuel JW, Sutherland MD, Belisle JT, Pascual DW. IL-17 Protects Against the Francisella tularensis Live Vaccine Strain, but not Against Virulent Type A F. tularensis. Infect Immun. 2013 Jun 17. [Epub ahead of print]
Loroño-Pino MA, García-Rejón JE, Machain-Williams C, Gomez-Carro S, Nuñez-Ayala G, Del Rosario Nájera-Vázquez M, Losoya A, Aguilar L, Saavedra-Rodriguez K, Lozano-Fuentes S, Beaty MK, Black WC 4th, Keefe TJ, Eisen L, Beaty BJ. Towards a Casa Segura: A Consumer Product Study of the Effect of Insecticide-Treated Curtains on Aedes aegypti and Dengue Virus Infections in the Home. Am J Trop Med Hyg. 2013 Jun 3. [Epub ahead of print]
de Lourdes Muñoz M, Mercado-Curiel RF, Diaz-Badillo A, Pérez Ramirez G, Black WC 4th. Gene flow pattern among Aedes aegypti populations in Mexico. J Am Mosq Control Assoc. 2013 Mar;29(1):1-18.
Shikani AH, Kourelis K, Alqudah MA, Shikani HJ, Cope E, Kirk N, Bergstedt D, Basaraba RJ, Leid JG. Multimodality topical therapy for refractory chronic rhinosinusitis: Our experience in thirteen patients with and twelve patients without nasal polyps. Clin Otolaryngol. 2013 Jun;38(3):254-8.
Quimby JM, Webb TL, Habenicht LM, Dow SW. Safety and efficacy of intravenous infusion of allogeneic cryopreserved mesenchymal stem cells for treatment of chronic kidney disease in cats: results of three sequential pilot studies. Stem Cell Res Ther. 2013 Apr 30;4(2):48.
Salazar FV, Achee NL, Grieco JP, Prabaripai A, Ojo TA, Eisen L, Dureza C, Polsomboon S, Chareonviriyaphap T. Effect of Aedes aegypti exposure to spatial repellent chemicals on BG-SentinelTM trap catches. Parasit Vectors. 2013 May 20;6(1):145
Barrera JS, Bernard F, Ehrhart EJ, Withrow SJ, Monnet E. Evaluation of risk factors for outcome associated with adrenal gland tumors with or without invasion of the caudal vena cava and treated via adrenalectomy in dogs: 86 cases (1993-2009). J Am Vet Med Assoc. 2013 Jun 15;242(12):1715-21.
Regan DP, Dubielzig RR, Zeiss CJ, Charles B, Hoy SS, Ehrhart EJ. Primary primitive neuroectodermal tumors of the retina and ciliary body in dogs. Vet Ophthalmol. 2013 May 15. doi: 10.1111/vop.12056.
Chaccour CJ, Kobylinski KC, Bassat Q, Bousema T, Drakeley C, Alonso P, Foy BD. Ivermectin to reduce malaria transmission: a research agenda for a promising new tool for elimination. Malar J. 2013 May 7;12:153. doi: 10.1186/1475-2875-12-153.
Olver CS, Nielsen VG. Thrombelastographic characterization of coagulation/fibrinolysis in horses: role of carboxyheme and metheme states. Blood Coagul Fibrinolysis. 2013 Apr;24(3):273-8.
Pabilonia KL, Cadmus KJ, Lingus TM, Bolte DS, Russell MM, Van Metre DC, Erdman MM. Environmental Salmonella in Agricultural Fair Poultry Exhibits in Colorado. Zoonoses Public Health. 2013 Jun 15. doi: 10.1111/zph.12056
Bai X, Feldman NE, Chmura K, Ovrutsky AR, Su WL, Griffin L, Pyeon D, McGibney MT, Strand MJ, Numata M, Murakami S, Gaido L, Honda JR, Kinney WH, Oberley-Deegan RE, Voelker DR, Ordway DJ, Chan ED. Inhibition of nuclear factor-kappa B activation decreases survival of Mycobacterium tuberculosis in human macrophages. PLoS One. 2013 Apr 25;8(4):e61925.
Kumar K, Awasthi D, Lee SY, Cummings JE, Knudson SE, Slayden RA, Ojima I. Benzimidazole-based antibacterial agents against Francisella tularensis. Bioorg Med Chem. 2013 Jun 1;21(11):3318-26.
Maillard JY, Bloomfield S, Coelho JR, Collier P, Cookson B, Fanning S, Hill A, Hartemann P, McBain AJ, Oggioni M, Sattar S, Schweizer HP, Threlfall J. Does Microbicide Use in Consumer Products Promote Antimicrobial Resistance? A Critical Review and Recommendations for a Cohesive Approach to Risk Assessment. Microb Drug Resist. 2013 Jun 14.
Kvitko BH, McMillan IA, Schweizer HP. An improved method for oriT-directed cloning and functionalization of large bacterial genomic regions. Appl Environ Microbiol. 2013 Jun 7.
Damron FH, McKenney ES, Barbier M, Liechti GW, Schweizer HP, Goldberg JB. Construction of Mobilizable Mini-Tn7 Vectors for Bioluminescent Detection of Gram-Negative Bacteria and Single-Copy Promoter lux Reporter Analysis. Appl Environ Microbiol. 2013 Jul;79(13):4149-53.
Pilon JL, Rhyan JC, Wolfe LL, Davis TR, McCollum MP, O'Rourke KI, Spraker TR, Vercauteren KC, Miller MW, Gidlewski T, Nichols TA, Miller LA, Nol P. Immunization with a Synthetic Peptide Vaccine Fails to Protect Mule Deer (Odocoileus hemionus) from Chronic Wasting Disease. J Wildl Dis. 2013 Jul;49(3):694-8.
Kuzmina TA, Kuzmin YI, Tkach VV, Spraker TR, Lyons ET. Ecological, morphological, and molecular studies of Acanthocheilonema odendhali (Nematoda: Filarioidea) in northern fur seals (Callorhinus ursinus) on St. Paul Island, Alaska. Parasitol Res. 2013 Jun 13. [Epub ahead of print]
Nichols TA, Spraker TR, Rigg TD, Meyerett-Reid C, Hoover C, Michel B, Bian J, Hoover E, Gidlewski T, Balachandran A, O'Rourke K, Telling GC, Bowen R, Zabel MD, Vercauteren KC. Intranasal Inoculation of White-Tailed Deer (Odocoileus virginianus) with Lyophilized Chronic Wasting Disease Prion Particulate Complexed to Montmorillonite Clay. PLoS One. 2013 May 9;8(5):e62455.
Lagana DM, Lee JS, Lewis JS, Bevins SN, Carver S, Sweanor LL, McBride R, McBride C, Crooks KR, Vandewoude S. Characterization of Regionally Associated Feline Immunodeficiency Virus (FIV) in Bobcats (Lynx rufus). J Wildl Dis. 2013 Jul;49(3):718-22.
Troyer RM, Thompson J, Elder JH, Vandewoude S. Accessory Genes Confer High Replication Rate of Virulent Feline Immunodeficiency Virus (FIV). J Virol. 2013 May 8. [Epub ahead of print]
Gallouzi IE, Wilusz J. A DIStinctively novel exoribonuclease that really likes U. EMBO J. 2013 Jun 11. doi: 10.1038/emboj.2013.136.
Schaffer PA, Weishaar KM, Han S. Endobronchial metastasis in a dog with sarcoma. J Vet Diagn Invest. 2013 Jun 19. [Epub ahead of print]
Hello everyone! My name is Rushika Perera and I recently joined the faculty of MIP. I am an RNA virologist interested in flaviviruses, their structure, replication and host interactions. My primary research is focused on the role of lipid metabolism in the virus life cycle within the human host and mosquito vector. I am very excited to be a part of AIDL / MIP. I did my graduate studies at the Markey Center for Structural Biology at Purdue University where I worked on the assembly of alphaviruses. For my post-doctoral studies I moved to the University of California at Irvine to work on host requirements for poliovirus replication. My interest in dengue virus brought me back to Purdue as a Research Scientist to pursue studies developing a systems biology approach to dengue virus infection focusing on lipids.
I am originally from Sri Lanka and moved to United States to pursue an undergraduate degree. I enjoy architecture, oil painting, and I have been a competitive Latin and ballroom dancer for over 20 years. I’m excited about moving to Fort Collins, working with MIP, and look forward to getting to know the CSU community.
The Annual MIP Spring Picnic was held on Friday, May 10 under mostly sunny skies, with only a few drops of rain after 5pm. As usual, the event was well attended by MIPers and their families who enjoyed delicious Famous Daves BBQ, listening to the LIVE Bluegrass Band, "In The Pines", while having their favorite MIP Department Head serve them a beer.
A big thank you to Ida Tieman, Cathy Griffin, Andrea Franson, and Jennifer Kahrs for organizing the event, and to the MSA and MSO students for their labor and financial help in making the picnic a success!
Check out the MIPicnic Photo Gallery
Congratulations to Claudia Gentry-Weeks, Christine Olver, Sandra Quackenbush, and Alan Schenkel for successfully competing for CVMBS College Research Council Awards!
Congratulations to Alan Schenkel, Carol Wilusz, Diane Ordway, Torsten Eckstein, Candace Mathiason and Glenda Taton-Allen for successfully competing for CVMBS Undergraduate Student Council Funding. They accounted for 5 of 8 awards granted and the funding will allow enhancement of our undergraduate teaching efforts.
Wondering what our recent Microbiology graduate students are doing with their degrees? Here's a snapshot of the future plans for some of our Spring 2013 graduates:
Claire Bounds will continue in her Quality Control Associate position at Amgen.
Christine Breivik and Joshua Brown will begin the Professional Master’s Program at CSU this fall.
Emma Gardner and Steven Woods have all been admitted to the Plan B MS program in MIP for the fall 2013 semester.
Steven Bruckbauer will begin Ph.D. study at the University of Wisconsin-Madison this fall.
Cortney Brumley will begin training at the Colorado Center for Medical Laboratory Sciences this summer.
Bianca Christensen will begin and MPH program at the University of Nebraska College of Public Health this fall.
Chloe Elder will be working at an orphanage in Johannesburg, South Africa this summer.
Alexander Emch will begin Ph.D. study at the University of Oregon Food Science and Safety program this fall.
Jordan Flatt will begin the Master’s program in microbiology at CSU this fall.
Donald Scott Gondzar is working as a consultant for the Pateros Brewing Company in Fort Collins.
Travis Green has accepted a position as a research associate in the laboratory of Dr. John Belisle.
Laura Heiberger will begin the master’s program in Stem Cell Biology at the University of Minnesota this fall.
Lauren Javernick (nee Bombardier) will begin medical school this fall at the Iowa Carver College of Medicine
Kendra Jones will begin the PhD program in microbiology at the Louisiana State Health Sciences Center this fall.
Laura Kapke has accepted a position as a Food Testing Laboratory Technician at Murray-Brown laboratories in Denver.
Ryan Knodle will begin medical school this fall at the University of Illinois-Chicago.
Hannah Laurence will be vet school this fall at the University of California-Davis.
Mengyan Li will begin graduate school at the Albert Einstein School of Medicine this fall.
Kelly Thompson is continuing her work at the Animal Population Health Institute.
Rebecca Timmons will begin vet school at CSU this fall.
Rachelle Reneau has been awarded the CDC Emerging Infectious Diseases (EID) Fellowship.
Parker Wilson will attend the Colorado School for Medical Laboratory Science this fall semester.
Brittany Wyatt will begin the PhD program in Biological Sciences at Marquette this fall.
The Spring Meeting of the Rocky Mountain Branch of the American Society for Microbiology was held April 12-13.
Check out the Photos from the Meeting
Congratulations to the following newly-elected members to the MIP Departmental Committees
Promotion, Tenure & Reappointment Committee
Graduate Education Committee
Undergraduate Education Committee
Best wishes to Austin Walton, student hourly for the department over the past three years, who recently earned his MBA from CSU and is moving to Boston, Massachusetts. Austin was a valued employee who supported our admin team in all three facilities, as well as completing special projects for labs in Pathology.
Best wishes to Eric Zuniga, student hourly for the department over the past five years, who recently earned his DVM/MBA from CSU and is moving to Texas to serve in the Army as a Veterinarian. Eric has helped the department with accounting to furniture moves, he was always willing to help with any task we asked of him.
The administrative staff held a farewell gathering on June 6 to wish both well in their future endeavors.
MIP researchers received a $500,000 grant from the Bill and Melinda Gates Foundation to study the transmission of tuberculosis in South Africa.
Dr. Diane Ordway, Dr. Ian Orme, and Research Associate Crystal Shanley visited the Airborne Infection Research Facility (AIR) in Witbank, South Africa, from March 17 – April 1. The AIR facility was established in 2005 by Harvard University Associate Professor Dr. Edward Nardell for research on preventing the transmission of tuberculosis from infected patients to healthcare workers.
The CSU study will investigate the immunological and pathological response of guinea pigs exposed to Mycobacterium tuberculosis in a setting that models natural human to human transmission.
During their time at the AIR facility, Drs. Ordway, Orme and Miss Shanley successfully trained local scientists on collecting and processing animal samples. The study’s samples will be sent to CSU Mycobacterial Research Laboratories for further research on the animals immune responses by flow cytometry and PCR cytokine analysis.
Recently, Dr. Matsie Mphahlele from the Medical Research Council S. Africa came to CSU to train on flow cytometry and qRT-PCR in CSU BSL-3 facilitates.
This research will coincide with similar investigations by colleagues at Harvard University and the Medical Research Council at the University of Pretoria, South Africa. Researchers hope to determine whether this experimental strategy proves to be more effective than traditional approaches on testing new experimental tuberculosis vaccines.
Plan to park on campus August 1, 2013 to July 31, 2014? If so, you will need to purchase or renew your parking permit by July 31, 2013. You can purchase your permit ONLINE starting July 1, 2013.
Also, be aware there will no longer be parking placards. Parking Services is transitioning to License Plate Recognition technology, which means all permit holders will need to register the license plates of any vehicles they may be driving to campus.
More information can be found at the CSU Parking & Transportation Services website.
Mark Your Calendars!
Go to the Rocky Mountain Virology Club website for more information.
The Prion Research Center has recently made it possible for internet surfers to learn about their research. Check out their new website and see what is happening in the Prion Research Center.
Contact Erin Napier if you are interested developing a website for your research group.
Congratulations to Forrest and Heather Ackart on the birth of their second child, Raedyn Chiyo Gale, born May 14 at 12:48pm. Forrest says "She was a quick one---only spent 36 minutes from walking into the hospital to a screaming little one and was a chunk at 9lbs 2oz and 20 inches long".
Congratulations to Brad and Grace Borlee on the birth of their daughter, Madison Olivia, on January 26th. Madison was born weighing 7 lbs 1 oz. and measuring 20 inches in length. Grace and Madison are both doing well.
Congratulations to Gregg Dean for coming in First Place in the Master Division in the Colorado Marathon held on May 5, 2013! He placed 29th overall, finishing the 26.2 mile race in 3 hours 4 minutes and 32 seconds.
MIP's very own Jenny Harding has finally come clean about her shoes. Read her public confession and watch her "favorites" video on K99's blog, How Many Pairs of Shoes Does Todd Harding’s Wife Jenny Own?
Ten years ago the MRL took a group photo at their Annual Retreat. Ten years later, as documented in the picture below, Lily is holding the 2003 photo. Notice anything peculiar? In an interesting coincidence, Lily is wearing exactly the same shirt that she wore 10 years (and doesn’t look like she’s changed a bit)!
If you are paid once a month, your payday for work in June will be on Monday, July 1 – a one business day delay. Please plan accordingly.
New Grant Awards
Randall Basaraba, "Disrupting Biofilm Formation to Improve TB Drug Treatment", NIH-NIAID.
Jeffrey Wilusz, "Characterization of a Novel Drug Target for the Development of BVDV Therapeutics", Boehringer Ingelheim Vetmedica, Inc.
Chester Moore, "Testing of Mosquito Pools for West Nile Virus", City of Fort Collins
Jeffrey Wilusz, "EAGER: Coupling of Transcription and mRNA Decay in Mammalian Cells", NSF - Biological Sciences
Lars Eisen, "Novel Vector Surveillance Trap for Flying Insects ", TDA Research, Inc.
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