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Colorado mountainsDow Laboratory

Selected Early and Recent Publications

Pub Med for Dow S.

  1. Mitchell LA, Hansen RJ, Beaupre AJ, Gustafson DL, Dow SW. (2013) Optimized dosing of a CCR2 antagonist for amplification of vaccine immunity. International Immunopharmacology15:357.
  2. Silva E and Dow S. (2013) Recent developments in Burkholderia vaccines. Frontiers in Medicine.
  3. Quimby J, Webb T, Habenicht L, and Dow S. (2013) Safety and efficacy of intravenous infusion of allogeneic cryopreserved mesenchymal stem cells for treatment of chronic kidney disease in cats: Results of 3 preliminary studies. Stem Cell Res Ther 4:48.
  4. Guth A, Elmslie R, Hafeman S, and Dow S. (2013) Liposomal clodronate for tumor macrophage depletion in dogs with soft tissue sarcoma. Vet Comp Oncol
  5. Skyberg J, Rollins M, Holderness J, Marlenee N, Dow S, and Pascual DW. (2012) Nasal acai polysaccharides potentiate innate immunity to protect against pneumonic Francisella tularensis and Burkholderia pseudomallei infection. PLoS Pathog
  6. Goodyear A, Bielefeldt-Ohmann H, Schweizer H, and Dow S. (2012) Persistent gastric colonization with Burkholderia pseudomallei and dissemination from the gastrointestinal tract following mucosal inoculation in mice. PLoS One.
  7. Sutherland MD, Goodyear AW, Troyer RM, Chandler JC, Dow SW, Belisle JT. (2012) Post-exposure immunization against Francisella tularensis membrane proteins augments protective efficacy of gentamicin in a mouse model of pneumonic tularemia. Vaccine. 30:4977-82.
  8. Michel B, Meyerett-Reid C, Johnson T, Ferguson A, Wyckoff C, Pulford B, Bender H, Avery A, Telling G, Dow S, Zabel MD. (2012) Incunabular immunological events in prion trafficking. Sci Rep. 2012;2:440.
  9. Kvitko BH, Goodyear A, Propst KL, Dow SW, Schweizer HP. (2012) Burkholderia pseudomallei known siderophores and hemin uptake are dispensable for lethal murine melioidosis. PLoS Negl Trop Dis.
  10. Habenicht LM, Webb TL, Clauss LA, Dow SW, Quimby JM. (2012) Urinary cytokine levels in apparently healthy cats and cats with chronic kidney disease. J Feline Med Surg.
  11. Guth A, Hafeman S, and Dow S. (2012) Depletion of myeloid cells triggers spontaneous T cell immunity against cancer. Oncoimmunology 1:1248
  12. Mitchell L, Hendersen A, and Dow S. (2012) Vaccine suppression by inflammatory monocytes. J Immunology 189:5612.
  13. Mitchell L, Dow S, Slansky J, and Biller B. (2012) Induction of remission results in spontaneous enhancement of anti-tumor cytotoxic T cell activity in dogs with lymphoma. Vet Immunol Immunopath 145:597-605.
  14. Webb T, Quimby J, and Dow S. (2012) In vitro comparison of feline bone marrow derived and adipose tissue derived mesenchymal stem cells. J Fel Med Surg 14:165-169.
  15. Hafeman S, Varland D, and Dow S. (2012) Bisphosphonates significantly increase the activity of doxorubicin or vincristine against canine histiocytosis cells. Vet Comp Oncol 10:44-60.
  16. Goodyear A, Troyer R, Bielefeldt-Ohmann, and Dow S. (2012) MyD88-dependent recruitment of monocytes and dendritic cells required for protection in mouse model of Burkholderia mallei pneumonia. Infection Immunity 80:110-120.
  17. Perry J, Thamm D, Avery A, and Dow S. (2011).  Increased monocyte chemoattractant protein-1 concentrations and monocyte count independent associate with reduced survival in dogs with lymphoma.  Vet Comp Oncol 9:55.
  18. Quimby J, Gibbons D, Webb T, and Dow S. (2011).  Evaluation of intra-renal mesenchymal stem cell injection for chronic kidney disease in cats: a pilot study. J Fel Med Surg, in press.
  19. Sottnik J, Rao S, Lafferty M, Withrow S, and Dow S. (2010) Association of blood monocyte and lymphocyte count and disease-free interval in dogs with osteosarcoma. J Vet Intern Med, 24:1439.
  20. U’Ren L, Guth A, and Dow S. (2010) Type I interferons inhibit the generation of tumor associated macrophages.  Cancer Immunol Immunoth 59:587-592.
  21. Jones A, Bosio C, Duffy A, Goodyear A, Schriefer M, and Dow S. (2010) Protection against pneumonic plague following oral immunization with a non-replicating vaccine.  Vaccine 28:5924.
  22. Propst K, Troyer R, Kellihan L, Schweizer H, and Dow S. (2010)  Immunotherapy markedly increases the effectiveness of antimicrobial therapy for treatment of Burkholderia pseudomallei infection.  Antimicrob Agents Chemoth 54:1785-1792.
  23. Goodyear A, Jones A, Troyer R, and Dow S.  (2010) Critical protective role for MCP-1 in pneumonic Burkholderia mallei infection.  J Immunol 184:1445-1454.
  24. Sottnik J, Guth A, Thamm D, and Dow S. (2010) Chronic bacterial osteomyelitis suppression of tumor growth requires innate immune responses. Cancer Immunol Immunother 59:367-375.
  25. Troyer R, Propst K, Fairman, J, Bosio K, and Dow S. (2009) Mucosal immunotherapy for protection from pneumonic Francisella infection. Vaccine 27:4424-4433.
  26. Goodyear A, Troyer R, Jones A, and Dow S. (2009) Protection from Burkholderia infection by inhalational immunotherapy.  Infection and Immunity 77:1759-1765.
  27. Guth A, Bosio C, Janssen W, Crouch E, Henson P, and Dow S. (2009) Lung environment determines unique phenotype of alveolar macrophages.  J. Physiol Lung Cell Mol Biol; 296:L936-946.
  28. Takeda T, Dow S, Miyahara N, Kodama T, Koya T, Taube C, Joetham A, Park J, Dakhama A, Kedl R, and Gelfand E. (2009) Vaccine-induced CD8+ T cell suppression of airway hyper-responsiveness and inflammation. J Immunol, 183:181-190.
  29. Elmslie R, Glawe P, and Dow S. (2009) Metronomic chemotherapy with cytoxan and piroxicam effectively delays tumor recurrence in dogs with incompletely resected soft tissue sarcoma, J Vet Intern Med, 22:1373-1379.
  30. Zaks K, Jordan M, Guth A, Sellins K, Kedl R, Izzo A, Bosio C, and Dow S. (2006) Efficient immunization and cross-priming by vaccine adjuvants containing TLR3 and TLR9 agonists complexed to cationic liposomes. J Immunol, 176:7335-7345.
  31. U’Ren L, Kedl R, and Dow S. (2006) Immunization with liposome-DNA complexes elicits enhanced antitumor immunity. Cancer Gene Ther, 13:1033-
  32. Bosio C and Dow S. (2005) Aberrant activation of pulmonary dendritic cells by Francisella tularensis. J Immunol 175:6792-6801.
  33. Dow SW, Liggitt DL, Fradkin L, and Potter TA. (1999) Potent immune activation and antitumor immunity induced by intravenous administration of cationic lipid-DNA complexes. J Immunol 163:1552-1561.