Christine S. Olver
Associate Professor

Phone: 491-1340 or 297-5112
Fax: 491-0603 or 297-4441
Email: Christine.Olver@Colostate.Edu
Office: 214 Pathology Building or 110 Diagnostic Medicine Center
Lab: 203 Pathology Building

Degrees

BS, University of North Carolina, 1983
DVM, The Ohio State University, 1987
PhD, The Ohio State University, 1994

Board Certifications

Diplomate, American College of Veterinary Pathologists, Clinical Pathology

Research Interests

Dr. Swardson was hired in late 1994 as a clinical pathologist with research interests of hematopoiesis, mechanisms of erythroid suppression in infectious diseases and macrophage:retrovirus interactions. She has changed research focus and now is involved in broader hematology studies including erythrocyte biology and serum proteomics for biomarker discovery.

Specifically her investigative efforts focus on:
• The role of the Duffy glycoprotein in Plasmodium yoelii infections
• The role of polymorphisms in the Duffy glycoprotein on the outcome of murine malaria infections
• Diagnosis of regenerative anemia in the horse.
• Maturation of reticulocytes: proteomic approaches

Selected Publications

Pub Med for Olver CS and Swardson CJ.

Kohn CW, Swardson CJ, Provost P, Gilbert RJ and Couto GC: Myeloid and megakaryocytic hypoplasia in related standardbreds. J Vet Intern Med 9:315-323, 1995.

Lichtenstein DL, Rushlow KE, Cook RF, Raabe ML, Swardson CJ, Kociba GJ, Issel CJ and Montelaro RC: Replication in vitro and in vivo of an equine infectious anemia virus (EIAV) mutant deficient in dUTPpase activity. J Virol 69:2881-2888, 1995.

Lassen ED and Swardson CJ. Hematology and Hemostasis in the horse: Normal functions and common abnormalities. In: Clinical Pathology, The Vet Clin North Amer, Equine Practice. Ed. by Messer NT. 11(3) 351-389, 1995.

Swardson CJ and Kociba GJ: Clonogenic haematopoietic progenitor assays from clinically normal horses. Comp Haematol Int 6:187-193, 1995.

Swardson CJ and Kociba GJ: Infection of bone marrow macrophages by equine infectious anemia virus: Cytopathic effect and induction of interleukin 6. Am J Vet Res 58:1402-1407, 1995.

Swardson CJ, Wassom DL, Avery AC: Plasmodium yoelii: Resistance to disease is linked to the MTV-7 locus in BALB.D2.Mlsa mice. Exp Parasitol 86:102-109, 1997.

Piercy RJ, Swardson CJ, Hinchcliff KW. Erythroid hypoplasia and anemia following administration of recombinant human erythropoietin to two horses. J Am Vet Med Assoc 212:244-247, 1998.

Sprague WS, Hackett TB, Johnson JS; Swardson-Olver, CJ, 2003, Hemochromatosis secondary to repeated blood tranfusions in a dog, Veterinary Pathology, 40:334-337.

Guilpin VO, Nosbisch L, Titus RG, and Swardson-Olver CJ, 2003, Infection with Leishmania major stimulates hematopoiesis in susceptible BALB/c mice and suppresses hematopoiesis in resistant CBA mice, Parasitology, 126(3):187-194.

Robert C. Burnett, William Vernau, Jaime F. Modiano, Christine S. Olver, Peter F. Moore, Anne C. Avery, 2003, Diagnosis of canine lymphoid neoplasia using clonal rearrangements of antigen receptor genes, Veterinary Pathology, 40(1):32-4.

Guilpin V*, Swardson-Olver C*, Nosbisch L, Titus R, 2002, Maxadilan, the vasodilator/immunomodulator from Lutzomyia longipalpis sand fly saliva, stimulates hematopoiesis in mice. Parasite Immunology 24(8): 437-446.

Swardson-Olver CJ, Dawson TC, Burnett RC, Maeda N, Peiper SC, Avery AC, 2002, Plasmodium yoelii uses the murine Duffy antigen-receptor for chemokines as a receptor for normocyte invasion and an alternative receptor for reticulocyte invasion, Blood 99 (8):2667-2684.