Yuanlin Peng, Ph.D.
Assistant Professor

Phone: (970) 491-0572
Fax: (970) 491-0623
Email:Yuanlin.Peng@colostate.edu
Office: 439 A Molecular and Radiological Biosciences Building

 

Degrees

• Ph.D., Radiological Health Sciences, Colorado State University, Colorado
• MS, Experimental Nuclear Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, China
• B.S., Biology, Beijing Normal University, China

Research Interests

Genetic Factors Affecting Susceptibility to Low Dose and Dose Rate Irradiation
This project addresses the identification of new (previously unknown) genes or polymorphic alleles of known genes affecting chromosomal radiosensitivity following low-dose and low dose-rate irradiation of human cells with gamma-rays. The emphasis is on genes and polymorphisms that can be directly demonstrated to affect ionizing radiation sensitivity in a way that is relevant for radiation carcinogenesis and risk assessment.

Selected Publications

• Joel S. Bedford, Hatsumi Nagasawa, Takamitsu A Kato, Paul F. Wilson, and Yuanlin Peng. Variations among Individuals in Cellular Radiasensitivity. Radiation Research. (In press).

• Bin Yan, Yuanlin Peng, and Chuan-Yuan Li. Molecular Analysis of Genetic Instability Caused by Chronic Inflammation. Methods in Molecular Biology, 152. (In press).

• Yu-Fen Lin, Hatsumi Nagasawa, Yuanlin Peng, Eric Y. Chuang, and Joel. S. Bedford. Comparison of Cellular Radiation Effects in Human MCF-10A Mammary Epithelial Cells Cultured as 2D Monolayers or 3D Acinar Stuctures in Matrigel: Cell killing, Chromosomal Aberration Production, and γ-H2AX Foci after Acute or Chronic Exposure to γ-Rays. Radiation Research. (In press).

• Yuanlin Peng, Thomas B. Borak, Simon D. Bouffler, Robert L. Ullrich, Michael M. Weil, and Joel S. Bedford. Radiation Leukemogenesis in Mice: Loss of PU.1 on Chromosome 2 in CBA/Ca and C57BL/6 Mice after Irradiation with 1 GeV/n 56Fe Ions or γ-Rays. Part II. Theoretical Considerations Based on Microdosimetry and the Initial Induction of Chromosome Aberrations. Radiation Research. (In press).

• Yuanlin Peng, Natalie Brown, Rosemary Finnon, Christy L. Warner, Xianan Liu, Paula C. Genik, Matthew A. Callan, F. Andrew Ray, Thomas B. Borak, Christophe Badie, Simon D. Bouffler, Robert L. Ullrich, Joel S. Bedford, and Michael M. Weil. Radiation Leukemogenesis in Mice: Loss of PU.1 on Chromosome 2 in CBA/Ca and C57BL/6 Mice after Irradiation with 1 GeV/n 56Fe Ions, X- or γ-rays. Part I. Experimental Observations. Radiation Research. (In press).