Selected Publications of Dr. Howard Liber
Kelsey, K.T., A. Memisoglu, D. Frenkel and H.L. Liber.
Human lymphocytes exposed to low doses of X-rays are less susceptible
to radiation-induced mutagenesis. Mutation Res., 263: 197-201 (1991).
Kelsey, K.T., K.J. Donohoe, B. Baxter, A. Memisoglu, J.B. Little, M. Caggana
and H.L. Liber. Genotoxic and mutagenic effects of the
diagnostic use of thallium 201 in nuclear medicine. Mutation Res., 260:
239-246. (1991).
Amundson, S.A. and H.L. Liber. A comparison of induced
mutation at homologous alleles of the tk locus in human cells. Mutation
Res., 247: 19-27.(1991).
Amundson, S.A. and H.L. Liber. A comparison of induced
mutation at homologous alleles of the tk locus in human cells. II. Molecular
analysis of mutants. Mutation Res., 267: 89-95 (1992).
Amundson, S.A., F. Xia, K. Wolfson and H.L. Liber. Different
cytotoxic and mutagenic responses induced by X-rays in two human lymphoblastoid
cell lines derived from a single donor. Mutation Res., 286: 233-241. (1993)
Denault, C.M. and H.L. Liber. The effects of hypoxia
and cysteamine on x-ray mutagenesis in human cells. I. Dose-response and
Southern blot analysis of induced mutants. Radiation Res., 135: 98-107
(1993).
Xia, F., S.A. Amundson, J.A. Nickoloff, and H.L. Liber.
Different recombinational repair capacities in closely related human lymphoblastoid
cell lines with different mutational responses to X-irradiation. Molec.Cell.
Biol., 14:5850-5857. (1994)
Xia, F., X. Wang, Y-H. Wang, N-M. Tsang, D.W. Yandell, K.T. Kelsey and
H.L. Liber. Altered p53 status correlates with differences
in sensitivity to radiation-induced mutation and apoptosis in two closely
related human lymphoblast lines. Cancer Research 55: 12-15. (1995)
Phillips, E.N., F. Xia, K.T. Kelsey and H.L. Liber. Spectra
of spontaneous and X-ray-induced mutations at the hprt locus in related
human lymphoblast cell lines that express wild-type or mutant p53. Radiation
Res., 143: 255-62. (1995)
Phillips, E.N., D. Gebow, and H.L. Liber. Spectra of
X-ray-induced and spontaneous intragenic hprt mutations in closely related
human cells differentially expressing the p53 tumor suppressor gene. Radiat.
Res., 147, 121-30. (1997)
Xia, F. and H.L. Liber. The tumor suppressor p53 modifies mutational
processes in a human lymphoblastoid cell line. Mutation Research,
373, 87-97. (1997)
Lippert, M.J., Q. Chen and H.L. Liber. Increased transcription
decreases the spontaneous mutation rate at the thymidine kinase locus
in human cells. Mutation Research, 401: 1-10. (1998)
Chuang, Y.-Y., Q. Chen and H.L. Liber. Radiation-induced
mutations at the autosomal thymidine kinase locus are not elevated in
p53-null cells. Cancer Research, 59: 3073-3076. (1999)
Gebow, D., N. Miselis and H.L. Liber. Homologous and
nonhomologous recombination resulting in deletion: Effects of p53 status,
microhomology, and repetitive DNA length and orientation. Molec. Cell.
Biol. 20:4028-4035. (2000)
Schwartz, J.L., J. Jordan, H.L. Liber, J.P. Murnane,
and H.H. Evans. p53-dependent chromosome instability is associated
with transient reductions in telomere length in immortal telomerase-positive
cell lines. Genes, Chromosomes, and Cancer, 30:236-244. (2001)
Peng, Y. Q. Zhang, H. Nagasawa, R. Okayasu, H.L. Liber,
and J.S. Bedford. DNA PKcs silencing by siRNA sensitizes human cells for
radiation-induced chromosome damage, cell killing and mutation. Cancer
Research 62:6400-6404. (2002)
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