Case #23 -- Immune-Mediated Hemolytic Anemia
Learning Objectives
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Case Presentation by:
Wade Shoemaker, Anneke Moresco and Angie MexasPatient Profile: "Junior", a 5-year old, castrated male Dachshund.
History:
"Junior" had been depressed for many days. He had vomited once and had some bloody diarrhea. He was now lethargic and anorectic.Physical Examination:
Heart rate = 120/minute. Pulse rate = 120/minute. Respiratory rate = 28/minute. Body weight = 8.4 kg. "Junior's" capillary refill time was normal but his gums were a little pale. Chest ausculted normally. Spleen was enlarged on abdominal palpation. Hematuria and melena were noted.Laboratory Findings:
Elevated white cell count (25,500/uL); neutrophilia with left shift (16,800/uL; 1300/uL bands); lymphopenia (300/uL); monocytosis (2300/uL). Regenerative anemia (3,710,000/uL; 333,900/uL reticulocytes). PCV = 26%. Platelets = 8000/uL. BUN = 5 mg/dL. Calcium = 8.4 mg/dL. Total protein = 4.4 gm/dL. Albumin = 2.2 gm/dL. AST = 42 IU/L. Potassium = 3.5 meq/L. Coombs test = positive.Questions: