Leslie M. Stone-Roy, PhD
Office: W326 Anatomy/Zoology Building
Currently, I teach blocks of lectures in Cellular Neurobiology (BMS 325), Functional Neuroanatomy (BMS 345) and Neuronal Circuits, Systems and Behavior (NB505). In addition, I have taught blocks of lectures in Developmental Neurobiology (NB503) and have coordinated Cellular Neurobiology and Techniques in Neuroscience (NB586).
My research efforts have focused on understanding the sense of taste, ranging from investigating the embryonic origins of taste receptor cells to the intracellular transduction mechanisms used by these cells. Most recently, our studies focused on investigating the roles of ATP and glutamate as neurotransmitters in the taste pathway.
Stone LM, Browning MD, Finger TE. 1994. Differential distribution of synapsins in the olfactory bulb. J Neurosci 14:301-309.
Stone LM, Finger TE, Tam PPL, Tan S-S. 1995. Taste receptor cells arise from local epithelium, not neurogenic ectoderm. Proc Nat Acad Sci USA 92:1916-1920.
Clapp TR, Stone LM, Margolskee RF, Kinnamon SC. 2001. Immunocytochemical evidence for co-expression of Type III IP3 receptor with signaling components of bitter taste transduction. BMC Neurosci 2:6-14.
Stone LM, Tan S-S, Tam PPL, Finger TE. 2002 Analysis of cell lineage relationships in taste buds. J Neurosci 22:4522-4529.
Stone LM, Wilcox CL, Kinnamon SC. 2002. Virus mediated transfer of foreign DNA into taste receptor cells. Chem Senses 27:779-787.
Finger TE, Danilova V, Barrows J, Bartel DL, Vigers AJ, Stone L, Hellekant G, Kinnamon SC. 2005. ATP signaling is crucial for communication from taste buds to gustatory nerves. Science 310:1495-1499.
Silver WL, Clapp TR, Stone LM, Kinnamon SC. 2006. TRPV1 receptors and nasal trigeminal chemesthesis. Chem Senses 31:807-812.
Stone LM, Barrows J, Finger TE, Kinnamon SC. 2007. Expression of T1Rs and gustducin in palatal taste buds of mice. Chem Senses 32:255-262.