Course Description: Mammalian digestive, endocrine, metabolic, renal, reproductive and respiratory systems physiology.
Course Objectives: Students will develop a thorough understanding of the regulation, function and integration of the various mammalian organ systems. The cellular basis for the behavior of these systems will be emphasized as appropriate, as well as the basis for system dysfunction.
Prerequisites: Six credits of biological science
Format: 4 credits - 4 hours of lecture per week
Semesters Offered: Spring
Coordinator: R. Anthony (coordinator), G. Seidel, L. Wilke and C. Vader-Lindholm
Text: Medical Physiology: A Cellular and Molecular Approach, Boron and Boulpaep
Course Outline:
| Week 1: | Introduction; overview of endocrine physiology; synthesis and secretion of hormones; regulation of growth and development - growth hormone | |
| Week 2: | Regulation of growth and development - thyroid hormone; endocrine regulation of Ca/P; GI structure and function; enteric nervous system and GI motility | |
| Week 3: | Pregastric physiology; gastric physiology; exocrine pancreas; liver and bile formation | |
| Week 4: | Hepatobiliary system; intestinal physiology; endocrinology of the absorptive state | |
| Week 5: | Endocrinology of the post-absorptive state; regulation of food intake and body weight | |
| Week 6: | Anatomy and embryology; sex chromosomes, differentiation of reproductive system | |
| Week 7: | Male reproduction; testis and sperm structure; male reproductive endocrinology; ovarian function | |
| Week 8: | Female reproductive cycles; ovulation and menopause; fertilization | |
| Week 9: | Embryonic development; fertilization and embryo technology; cloning; implantation, placenta | |
| Week 10: | Maternal physiology of pregnancy; parturition and lactation; organization of the urinary system; glomerular filtration and renal clearance | |
| Week 11: | Glomerular filtration and renal clearance; overview of tubular function; transport of Na and Cl | |
| Week 12: | Transport of Na and Cl; K transport; urinary concentration and dilution; transport of acids and bases | |
| Week 13: | Integration of salt and water balance; functional anatomy of the pulmonary system; mechanics of respiration | |
| Week 14: | Mechanics of respiration; gas transport; gas exchange; ventilation/perfusion relationships | |
| Week 15: | Ventilation/perfusion relationships; control of ventilation; pulmonary function/altitude |
Link to Course Materials for public use
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